A0A7K6JSR2 · A0A7K6JSR2_9PASE
- ProteinPolyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6
- GenePlpp6
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids215 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- (2E)-geranyl diphosphate + H2O = (2E)-geranyl phosphate + H+ + phosphateThis reaction proceeds in the forward direction.
- (2E)-geranyl phosphate + H2O = (2E)-geraniol + phosphateThis reaction proceeds in the forward direction.
- (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesyl phosphate + H+ + phosphateThis reaction proceeds in the forward direction.
- (2E,6E)-farnesyl phosphate + H2O = (2E,6E)-farnesol + phosphateThis reaction proceeds in the forward direction.
- (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (2E,6E,10E)-geranylgeranyl phosphate + H+ + phosphateThis reaction proceeds in the forward direction.
- (2E,6E,10E)-geranylgeranyl phosphate + H2O = (2E,6E,10E)-geranylgeraniol + phosphateThis reaction proceeds in the forward direction.
- 1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphateThis reaction proceeds in the forward direction.
- H2O + presqualene diphosphate = H+ + phosphate + presqualene phosphateThis reaction proceeds in the forward direction.
- H2O + presqualene phosphate = phosphate + presqualene alcoholThis reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Cellular Component | nuclear inner membrane | |
Molecular Function | hydrolase activity | |
Biological Process | lipid metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Passeriformes > Passeroidea > Paramythiidae > Oreocharis
Accessions
- Primary accessionA0A7K6JSR2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 89-110 | Helical | ||||
Sequence: LLNLLFALLLDLVMVAVVKGLV | ||||||
Transmembrane | 152-172 | Helical | ||||
Sequence: LVLAVPLRVLVVLWALIVSIS | ||||||
Transmembrane | 192-214 | Helical | ||||
Sequence: YALYGVVEHCWLSPATAPALFAL |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 88-199 | Phosphatidic acid phosphatase type 2/haloperoxidase | ||||
Sequence: VLLNLLFALLLDLVMVAVVKGLVKRPRPTHNKMDMFVTISVDKYSFPSGHATRAALVCRFVLRHLVLAVPLRVLVVLWALIVSISRVMLGRHNMTDVLFGLLLGYALYGVVE |
Sequence similarities
Belongs to the PA-phosphatase related phosphoesterase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length215
- Mass (Da)23,194
- Last updated2021-04-07 v1
- ChecksumC72B308CCF1CF9AB
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: S | ||||||
Non-terminal residue | 215 | |||||
Sequence: W |
Keywords
- Technical term