A0A7K6AQG2 · A0A7K6AQG2_UPUEP

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • (5S,12S)-dihydroxy-(6E,10E,12E,14Z)-eicosatetraenoate + NADP+ = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + H+ + NADPH
    This reaction proceeds in the forward direction.
  • 20-hydroxy-leukotriene B4 + NADP+ = 12-oxo-20-hydroxy-leukotriene B4 + H+ + NADPH
    This reaction proceeds in the forward direction.
  • 4-hydroxynonanal + NADP+ = (E)-4-hydroxynon-2-enal + H+ + NADPH
    This reaction proceeds in the backward direction.
  • 6-trans-leukotriene B4 + NADP+ = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + H+ + NADPH
    This reaction proceeds in the forward direction.
  • NADP+ + nonan-2-one = (3E)-nonen-2-one + H+ + NADPH
    This reaction proceeds in the backward direction.
  • NADP+ + octanal = (2E)-octenal + H+ + NADPH
    This reaction proceeds in the backward direction.
  • NADP+ + pentan-2-one = (E)-pent-3-en-2-one + H+ + NADPH
    This reaction proceeds in the backward direction.
  • an n-alkanal + NADP+ = an alk-2-enal + H+ + NADPH
    This reaction proceeds in the backward direction.
    EC:1.3.1.74 (UniProtKB | ENZYME | Rhea)
  • decanal + NADP+ = (2E)-decenal + H+ + NADPH
    This reaction proceeds in the backward direction.
  • dodecanal + NADP+ = (2E)-dodecenal + H+ + NADPH
    This reaction proceeds in the backward direction.
  • hexanal + NADP+ = (E)-hex-2-enal + H+ + NADPH
    This reaction proceeds in the backward direction.
  • leukotriene B4 + NADP+ = 12-oxo-leukotriene B4 + H+ + NADPH
    This reaction proceeds in the forward direction.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function13-prostaglandin reductase activity
Molecular Function15-oxoprostaglandin 13-oxidase activity
Molecular Function2-alkenal reductase [NAD(P)+] activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Prostaglandin reductase 1
  • EC number
  • Alternative names
    • Dithiolethione-inducible gene 1 protein
    • Leukotriene B4 12-hydroxydehydrogenase
    • NAD(P)H-dependent alkenal/one oxidoreductase

Gene names

    • Name
      Ptgr1
    • ORF names
      UPUEPO_R08572

Organism names

  • Taxonomic identifier
  • Strain
    • B10K-DU-012-37
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Upupiformes > Upupidae > Upupa

Accessions

  • Primary accession
    A0A7K6AQG2

Proteomes

Subcellular Location

PTM/Processing

Keywords

Interaction

Subunit

Monomer or homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-259Enoyl reductase (ER)

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    260
  • Mass (Da)
    28,207
  • Last updated
    2021-04-07 v1
  • Checksum
    B2BF728A44ABB05F
INRIVESKNAAFTVGTFVLGRSGWRTHFISNGNDLQLLPSSWPESLPKSLALGTVGMPGLTAYFGLMEVCKMKPGETVLVNAAAGAVGNVVGQLAKIGGCKVVGCAGSDDKVAYLKKIGFDEAFNYKTVTSLDDALHKASPDGYDCFFDNVGGEFASIAVNHMKKYGRIAVCGAISQYNDSVPQKGTYIQMPVIFKELRIEGFIVSRWNNRREEGLKALLKWVVEGKVKYQEHITEGFENMPAAFIAMLKGDNLGKAIVK

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue260

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VZRI01004118
EMBL· GenBank· DDBJ
NWU92290.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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