A0A7K5B0K1 · A0A7K5B0K1_9FURN

  • Protein
    adenylate cyclase
  • Gene
    Adcy2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site301Mg2+ 1 (UniProtKB | ChEBI); catalytic
Binding site301Mg2+ 2 (UniProtKB | ChEBI); catalytic
Binding site301-306ATP (UniProtKB | ChEBI)
Binding site302Mg2+ 2 (UniProtKB | ChEBI); catalytic
Binding site343-345ATP (UniProtKB | ChEBI)
Binding site345Mg2+ 1 (UniProtKB | ChEBI); catalytic
Binding site345Mg2+ 2 (UniProtKB | ChEBI); catalytic
Binding site389ATP (UniProtKB | ChEBI)
Binding site950ATP (UniProtKB | ChEBI)
Binding site1030-1032ATP (UniProtKB | ChEBI)
Binding site1037-1041ATP (UniProtKB | ChEBI)
Binding site1077ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionadenylate cyclase activity
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Biological ProcesscAMP biosynthetic process
Biological Processintracellular signal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    adenylate cyclase
  • EC number

Gene names

    • Name
      Adcy2
    • ORF names
      FURFIG_R02870

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • B10K-DU-003-06
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Passeriformes > Furnariidae > Furnarius

Accessions

  • Primary accession
    A0A7K5B0K1

Proteomes

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane52-76Helical
Transmembrane82-102Helical
Transmembrane114-137Helical
Transmembrane143-159Helical
Transmembrane166-187Helical
Transmembrane193-213Helical
Transmembrane606-627Helical
Transmembrane633-658Helical
Transmembrane686-707Helical
Transmembrane742-763Helical
Transmembrane770-788Helical
Transmembrane813-831Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain296-423Guanylate cyclase
Domain898-1043Guanylate cyclase

Sequence similarities

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    1,102
  • Mass (Da)
    125,071
  • Last updated
    2021-04-07 v1
  • Checksum
    87034598A0FC2DE5
MWQEAMMMRRRRRYLLERADQAGGGCGAGGEQSRSRDWLYESYYCMSQQHPLIVFLLLIVMGACLALLAVFFASGLEVEEHVAFLITVPTALAIFFAIFILVCVEPVFKKLLRIFSLVVWVCLVAMGYLFMCFGGIICPWDQVSFFLFIIFVVYTMLPFNMRDAIVASVLTSASHTIVLSVCLSGTAVVKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQLENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLQNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITSVTLAHLNGAYKVEDGDGDVRDPYLKEHNVKTYFVINPKGEKRSPQHHIRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQYHFQRCRERTKSQKRRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKTLEKEYRATTLPAFKYYVTCACLIFFCIFVVQILVLPKTSILGISFGAAFLLLSFILFVCFAGQLLQCSKKASASLLWILKSSGIIANRPWPRITLTLTTTAIILTMAIFNMFFLDNAVIAFPSVLNSSNASFPNSSNQTRWCIQNNCFFLPYFIYSCILGLISCSVFLRINYELKMVIMLIALVGYNVILLHTHGPMLDDYSKFMYAMAPLRRPGILKDLKTMGSISLFIFFITLLVLGRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARNLKNEDLYHQSYDCVCVMFASVPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSATPNQEQCQEPERQYMHIGTMVEFAFALVAKLDVINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETNNVLKTLGYMSTCRGIINVKGKGELKTYFVHTEMTRSLSQGNVAS

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue1102

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VYZD01000314
EMBL· GenBank· DDBJ
NWR89107.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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