A0A7K2S6Y8 · A0A7K2S6Y8_9ACTN
- ProteinFluoride-specific ion channel FluC
- GenefluC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids124 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces
Accessions
- Primary accessionA0A7K2S6Y8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 32-52 | Helical | ||||
Sequence: VFPWGTFAANAGGALFLGFLA | ||||||
Transmembrane | 64-82 | Helical | ||||
Sequence: LNLLLATGFCGALSTWSTF | ||||||
Transmembrane | 102-123 | Helical | ||||
Sequence: LLLTVGAGVGLSFGGAAVANAA |
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length124
- Mass (Da)12,729
- Last updated2021-04-07 v1
- ChecksumA2536212587B0D00