A0A7H9HYR8 · A0A7H9HYR8_9SACH
- Protein2-hydroxyacyl-CoA lyase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids556 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- a 2-hydroxy-3-methyl fatty acyl-CoA = a 2-methyl-branched fatty aldehyde + formyl-CoAThis reaction proceeds in the forward direction.
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | catalytic activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | thiamine pyrophosphate binding | |
Biological Process | fatty acid alpha-oxidation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2-hydroxyacyl-CoA lyase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Torulaspora
Accessions
- Primary accessionA0A7H9HYR8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-117 | Thiamine pyrophosphate enzyme N-terminal TPP-binding | ||||
Sequence: RIADYFTELLQDYGIETVFGIVGIPIVELANAMIAKGIRFIACRNEQSASYAASAYGYLTGKPGVLLVVGGPGLIHSLAGIYNSMSNKWPLVVIAGSTEDPYKGGFQELDQISL | ||||||
Domain | 191-321 | Thiamine pyrophosphate enzyme central | ||||
Sequence: ARVADLLSGSKNKRVLLVIGKGVVDHSVQLRKFVDEFNVPFLPTPMAKGVVPDSHPLNVSSARSKALKEAEIVLILGARLNWILHYGQAPKWNSNAIFVQVDSDPASLGQNNSAGLTYALCGDLELTLKQL | ||||||
Domain | 386-534 | Thiamine pyrophosphate enzyme TPP-binding | ||||
Sequence: GANTMDIARISFPTDYPKHRLDAGTNATMGIGLGYAIAAKLSNPDKDVVLIQGDSAFGFSAMELETAARNQLALVVIVMNNSGIYHGTEQEPTSQVPSTALSKECRYDLVGKGLGTNGCIVRNLIDLKVAFQRALNASRNNKRSTVINV |
Sequence similarities
Belongs to the TPP enzyme family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length556
- Mass (Da)60,459
- Last updated2021-02-10 v1
- Checksum90C7899C61765D76
Keywords
- Technical term