A0A7G7FN58 · A0A7G7FN58_9BACI

Function

function

Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site.

158850100150200250300350400450500550
TypeIDPosition(s)Description
Binding site177L-aspartate (UniProtKB | ChEBI)
Binding site223L-aspartate (UniProtKB | ChEBI)
Binding site223-225ATP (UniProtKB | ChEBI)
Binding site232ATP (UniProtKB | ChEBI)
Binding site451L-aspartate (UniProtKB | ChEBI)
Binding site485ATP (UniProtKB | ChEBI)
Binding site492L-aspartate (UniProtKB | ChEBI)
Binding site537-540ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionaspartate-tRNA ligase activity
Molecular FunctionATP binding
Molecular Functionnucleic acid binding
Molecular Functiontransferase activity
Biological Processaspartyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aspartate--tRNA ligase
  • EC number
  • Alternative names
    • Aspartyl-tRNA synthetase
      (AspRS
      )

Gene names

    • Name
      aspS
    • ORF names
      HUW50_01495

Organism names

Accessions

  • Primary accession
    A0A7G7FN58

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain146-558Aminoacyl-transfer RNA synthetases class-II family profile
Region201-204Aspartate

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    588
  • Mass (Da)
    66,219
  • Last updated
    2021-02-10 v1
  • Checksum
    2F66AB59CB57946E
MFGRTYYCGEVPESAIGEKIVLKGWVQKRRDLGGVIFIDLRDRTGVVQIVFNPEISEEALAIAERVRSEYVLDITGKVVERDAETVNPNVPTGKIEVIVENVTIINAAKNPPFLIEDKSDEVSEDVRLKYRYLDLRRPALFNTIQMRHNVTKSMRNFLDESGFLDIETPILTKSTPEGARDYLVPSRVHEGEFYALPQSPQIFKQLLMVSGFDKYYQIARCFRDEDLRADRQPEFTQIDIEASFMSQDDIMSMTEKMMARIMKETKGVEINLPMQRMPYDEAMGRFGSDKPDTRFGLELVDVGEIVKDSGLKVFSSVVANGGQVKSINVKGAADKYSRKDMDALAEFVAPYGAKGLAWLKVEEDGLKGPIIKFFTEEEQKGLVRTMEATVGDLLVFVADKKSVVADSLGALRLKLGKDLQLIDESKYNFLWVVDWPLLEYDEATKRYYAAHHPFTMPAREDLSLFDTDPGNMKAQAYDIVLNGYELGGGSIRIFEKDVQEKMFKLLGFSDEEAKEQFGFLLDAFEYGTPPHGGIALGLDRLVMLLAGRTNLRDTIAFPKTASASDLLTNAPSTVSEAQLEELNLELRD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP055263
EMBL· GenBank· DDBJ
QNF26342.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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