A0A7C2Z1S5 · A0A7C2Z1S5_9AQUI

  • Protein
    Homoserine kinase
  • Gene
    thrB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.

Features

Showing features for binding site.

130120406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site84-94ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionhomoserine kinase activity
Biological Processthreonine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Homoserine kinase
  • EC number
  • Short names
    HK
    ; HSK

Gene names

    • Name
      thrB
    • ORF names
      ENO47_02390

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SpSt-132
  • Taxonomic lineage
    Bacteria > Aquificota > Aquificia > Aquificales > Aquificaceae > Hydrogenobacter

Accessions

  • Primary accession
    A0A7C2Z1S5

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain80-137GHMP kinase N-terminal
Domain200-274GHMP kinase C-terminal

Sequence similarities

Belongs to the GHMP kinase family. Homoserine kinase subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    301
  • Mass (Da)
    32,962
  • Last updated
    2020-12-02 v1
  • Checksum
    0D353D9630A84920
MLKIKVPASTSNFGSGFDAFGLALSLYNEFYVEPSGSYNVQIEGEGSNLPTDEENLFIKVYKRACKTLGKEEVPISLKQINRVPTARGLGSSATAIVGGILACQALHGLDISLEEKLKIAFEFERHPDNLLPAFLGGFVVCASTEEEVKFIRLGFPKEIKVVVCVPDFELSTEKAREVIKKEVSLKDAVFNLQRSALFVASLLSKNFELLKEAVKDRLHQPYRAHLIPGFWQVLEEAYKFGALAVFLSGAGPSVASLCLDKMEEVGKAMVKAFEDAGVKAKYMVLEVAEEGALVEYEGSNP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DSFP01000028
EMBL· GenBank· DDBJ
HEW45509.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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