A0A7C2Z1S5 · A0A7C2Z1S5_9AQUI
- ProteinHomoserine kinase
- GenethrB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids301 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
Catalytic activity
- ATP + L-homoserine = ADP + H+ + O-phospho-L-homoserine
Pathway
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | homoserine kinase activity | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHomoserine kinase
- EC number
- Short namesHK ; HSK
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Aquificota > Aquificia > Aquificales > Aquificaceae > Hydrogenobacter
Accessions
- Primary accessionA0A7C2Z1S5
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 80-137 | GHMP kinase N-terminal | ||||
Sequence: INRVPTARGLGSSATAIVGGILACQALHGLDISLEEKLKIAFEFERHPDNLLPAFLGG | ||||||
Domain | 200-274 | GHMP kinase C-terminal | ||||
Sequence: ASLLSKNFELLKEAVKDRLHQPYRAHLIPGFWQVLEEAYKFGALAVFLSGAGPSVASLCLDKMEEVGKAMVKAFE |
Sequence similarities
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length301
- Mass (Da)32,962
- Last updated2020-12-02 v1
- Checksum0D353D9630A84920