A0A7C0XB95 · A0A7C0XB95_UNCW3
- ProteinUDP-N-acetylmuramate--L-alanine ligase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids439 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- UDP-N-acetyl-alpha-D-muramate + L-alanine + ATP = UDP-N-acetyl-alpha-D-muramoyl-L-alanine + ADP + phosphate + H+
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UDP-N-acetylmuramate-L-alanine ligase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylmuramate--L-alanine ligase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacteria division WOR-3
Accessions
- Primary accessionA0A7C0XB95
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 7-106 | Mur ligase N-terminal catalytic | ||||
Sequence: KIHMVGIGGSGMSGIAEVLHNLGFMVTGSDIQRKDITERLEKLGIKIFYGHAPENVEGAEVVVVSTAIPPDNPEVLYAHEKKIPVIPRAEMLAELMRMKY | ||||||
Domain | 110-289 | Mur ligase central | ||||
Sequence: VSGAHGKTTTTSMIASILEKAGYDPTVVVGGRIRGMGTGGKLGQSEYLVAEADESDGSFLKLFPTISVITNIDEEHIDTYGDMENLKNAFIEFANKVPFYGCTVISIDDPGARELLPRIKRRVLTFGLSRQADFEARELELKGLGSSYSLYVRGEPMGKVRLGVPGIFNVRNSLAAFATA | ||||||
Domain | 311-439 | Mur ligase C-terminal | ||||
Sequence: RRFEIKGEKKGIMVVDDYAHHPVEIEAVLKAARRFWEGRIIVLFQPHRYSRTRRLYRRFGSAFHLADILIVTSIYPAGEKPLPGVTSELIYNAARDAGHREVYLIEDLDEAGKFLLETLKEGDLVITMG |
Family and domain databases
Sequence
- Sequence statusFragment
- Length439
- Mass (Da)48,612
- Last updated2020-12-02 v1
- Checksum6C79BC9EF49BA13E
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 439 | |||||
Sequence: G |