A0A6P4B7E1 · A0A6P4B7E1_ZIZJJ

Function

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Probably binds two magnesium or manganese ions per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site, active site, site.

156750100150200250300350400450500550
TypeIDPosition(s)Description
Binding site313Mg2+ 1 (UniProtKB | ChEBI)
Binding site344Mg2+ 1 (UniProtKB | ChEBI)
Active site420
Active site460Proton donor/acceptor
Binding site460Mg2+ 1 (UniProtKB | ChEBI)
Binding site462Mg2+ 1 (UniProtKB | ChEBI)
Site462Transition state stabilizer
Site532Important for catalytic activity
Binding site557Mg2+ 1 (UniProtKB | ChEBI)
Active site558Proton acceptor
Binding site558Mg2+ 1 (UniProtKB | ChEBI)
Site558Interaction with DNA substrate

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA binding
Molecular FunctionDNA-(apurinic or apyrimidinic site) endonuclease activity
Molecular Functiondouble-stranded DNA 3'-5' DNA exonuclease activity
Molecular Functionendonuclease activity
Molecular Functionlyase activity
Molecular Functionmetal ion binding
Molecular Functionphosphoric diester hydrolase activity
Biological Processbase-excision repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-(apurinic or apyrimidinic site) endonuclease
  • EC number

Gene names

    • Name
      LOC107431641

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Rosales > Rhamnaceae > Paliureae > Ziziphus

Accessions

  • Primary accession
    A0A6P4B7E1

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain123-157SAP

Sequence similarities

Belongs to the DNA repair enzymes AP/ExoA family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    567
  • Mass (Da)
    63,100
  • Last updated
    2020-12-02 v1
  • Checksum
    00C05A8043E9E437
MASVLKSETDCETLFGGCSPKPCCQSANLRRRSMLTYAAVAPGSFRIAALVSLRVSKSAMGSRRPISSSSRPILAISEDKKKDKPLKGLMATNPNLEKPVIKEHGAESSSDEFESFKDDPSSIEKMTVQELRTTLRRVGVPAKGSKRDLVSALKVYAAKKINGEHCQMTEDKILSISAESLSEDREDENLYDEDGVKNVSAFSEVHGIQRSKRRLKQSGVEYKVVTTRQKLSAKTDEVSGGKLSRTKRKVSSESATVGVKTDEEVNTPTMESEPWTVLAHKKPQKGWIPYNPKTMRPPPLNGDTKSVKLMSWNVNGLRALLKLEGFSALELAQREDFDVLCLQETKLQEKDIEGIKRSLIDGYENSFWTCSVSKLGYSGTAIISRIKPLSVRYGLGIADHDSEGRLVTAEFDSFYLISGYVPNSGDGLKRLSYRVTEWDTSLSNYMKELEKSKPVVLTGDLNCAHEEIDIFNPAGNKRSAGFTDEERQSFGTNFLSKGFVDTFRRQHPGVVGYTYWGYRHNGRKTNKGWRLDYFLVSESIADKVHDSYILPDVTGSDHCPIGLVLEL

Computationally mapped potential isoform sequences

There are 6 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A6P4AP58A0A6P4AP58_ZIZJJLOC107431641585
A0A6P4ARM9A0A6P4ARM9_ZIZJJLOC107431641544
A0A6P6GMR2A0A6P6GMR2_ZIZJJLOC107431641508
A0A6P6GN13A0A6P6GN13_ZIZJJLOC107431641537
A0A6P4AK09A0A6P4AK09_ZIZJJLOC107431641545
A0A6P6GSA0A0A6P6GSA0_ZIZJJLOC107431641538

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

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