A0A6P0RV05 · A0A6P0RV05_9CYAN

  • Protein
    Octanoyltransferase
  • Gene
    lipB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

Miscellaneous

In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Pathway

Protein modification; protein lipoylation via endogenous pathway; protein N6-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.

Features

Showing features for binding site, site, active site.

TypeIDPosition(s)Description
Binding site77-84substrate
Site141Lowers pKa of active site Cys
Binding site144-146substrate
Binding site157-159substrate
Active site175Acyl-thioester intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentribonuclease MRP complex
Molecular Functionlipoyl(octanoyl) transferase activity
Biological Processprotein lipoylation
Biological ProcessrRNA processing
Biological ProcesstRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Octanoyltransferase
  • EC number
  • Alternative names
    • Lipoate-protein ligase B
    • Lipoyl/octanoyl transferase
    • Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase

Gene names

    • Name
      lipB
    • ORF names
      F6K21_15875

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SIO2D2
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Oscillatoriophycideae > Oscillatoriales > Microcoleaceae > Symploca

Accessions

  • Primary accession
    A0A6P0RV05

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain35-213BPL/LPL catalytic

Sequence similarities

Belongs to the LipB family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    216
  • Mass (Da)
    24,482
  • Last updated
    2020-10-07 v1
  • Checksum
    1DA6427D9212A45B
MVLPRRCCLYNQDLVPYAVAWEQQLSLVTERIQDPSLDDVLLLLEHPAVYTLGRGASLEFLKFDPNVVDFPTYRVERGGEVTYHCPGQLVGYPILNLRYYQQDLHWYLRQLEEVLIQLLGIYGLKGERITGMTGVWLEGRKVAAIGIKASRWITMHGFALNVCPELSGFEKIVPCGIANKPVGSLAQFIPGIRVEQVRHLVATKFAQVFNVELIQI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAHGQ010000211
EMBL· GenBank· DDBJ
NEQ66950.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp