A0A6L8DJM3 · A0A6L8DJM3_UNCGE

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site236Mg2+ (UniProtKB | ChEBI)
Binding site266Mg2+ (UniProtKB | ChEBI)
Binding site268Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • Name
      aceE
    • ORF names
      F4132_05950

Organism names

Accessions

  • Primary accession
    A0A6L8DJM3

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain205-299Transketolase N-terminal
Domain484-705Pyruvate dehydrogenase E1 component middle

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    893
  • Mass (Da)
    99,968
  • Last updated
    2020-10-07 v1
  • Checksum
    BABD8FC5AE43EB64
MTQDTSRSEYEIDLDRVESLEWLESLDYVLQHSGPGRVRQLIAQLQAHARGKGVRLPFAENTPYINTIPPDQQPPYPGSDELEHRIRNIIRWNAMAMVVRANTADKSLGGHIATYASVCNLYEVGFNHFFRGPGEGYDGDQIFFQPHSSPGIYARAYIEGRFNEQHLDNFRRELRPGGGLSSYPHPWLMPDFWIFPTASMGLSAIMSIYQARFNRYLEDRGLKQGNGCKVWAFLGDGETDEPEALGAITLAAREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEAAFHGAGWNVIKVIWGSGWDPLLAQDDEGLLVKRMGEIVDGQYQKYTVSDGKYQRDHFFGVHPKLMEMSRLLTDEHVRTIIRGGHDQEKIYAAYKAAVEHPGAPTVILAKTIKGYGLGEWGEGKNTAHQQKMIDEEGLRHLRTELGIPLSDDEVREAPYFRPSADSAEMEYIRERRESLGGYIPRRNVVNPGLPAAPPDEVFEEFKAGTDGREVSTTMVFTRMLSRLLREPEIGKLIVPIVPDEARTFGMEALFRQCGIYSHAGQLYEPVDIDTLLYYKEAQDGQILEEGITEAGSLSSFVAAGTAYSTHGVNTIPFFIFYSMFGLQRVGDLIWAAAEMRTRGFLLGGTAGRTTLNGEGLQHQDGQSHLLADPVPNLLTYDPAYAYELATIIKDGIRRMYVDQEDLFYYITVQNENYAMPSMPEGVEEGILKGMYRLSTLNGGTAKAHLFGSGSIINESLKAQEMLAEDFGVEADVWSVTSYKQLRRDAMETERWNLLHPSESPRVPYVTACLEDTGGVYVMASDYVRTLPDSIARWVPGPVVSLGTDGFGRSDSRPALRNFFEMDARFITLGTLNALARKGDLSPEVPERAMRKLEIDPEKANPLDV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VYCK01000019
EMBL· GenBank· DDBJ
MYH18639.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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