A0A6H1UE82 · A0A6H1UE82_9GAMM
- Proteinasparagine synthase (glutamine-hydrolyzing)
- GeneasnB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids554 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H+
Pathway
Amino-acid biosynthesis.
Features
Showing features for active site, binding site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 2 | For GATase activity | ||||
Sequence: C | ||||||
Binding site | 99 | L-glutamine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 233 | ATP (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 273 | ATP (UniProtKB | ChEBI) | ||||
Sequence: I | ||||||
Binding site | 347-348 | ATP (UniProtKB | ChEBI) | ||||
Sequence: SG | ||||||
Site | 349 | Important for beta-aspartyl-AMP intermediate formation | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | asparagine synthase (glutamine-hydrolyzing) activity | |
Molecular Function | ATP binding | |
Biological Process | asparagine biosynthetic process | |
Biological Process | glutamine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameasparagine synthase (glutamine-hydrolyzing)
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Ferrimonadaceae > Ferrimonas
Accessions
- Primary accessionA0A6H1UE82
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-186 | Glutamine amidotransferase type-2 | ||||
Sequence: CGIFAIVDIKTDPQALRHSALKLARTLRHRGPDWSGIYADDYAILAHERLAIVDVETGAQPLISPDGNVVLAVNGEIYNHRELREELAVGYQFQTGSDCEVILALYLKYGTDFLDKLNGIFAFVLWDANKGKYLVGRDHLGIIPLYQGFDEHGNRYFASEMKALVPVCNQISEFLPGQYFDSRRK |
Sequence similarities
Belongs to the asparagine synthetase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length554
- Mass (Da)62,090
- Last updated2020-08-12 v1
- Checksum19E06A33D48D1758
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP051180 EMBL· GenBank· DDBJ | QIZ76939.1 EMBL· GenBank· DDBJ | Genomic DNA |