A0A6G9KJK9 · TX10A_MANRB

Function

function

Induces paralysis after injection into blowflies (L.caesar) (PubMed:32182430).
In most cases is not lethal 24 hours after injection, but paralysis is irreversible (PubMed:32182430).
May have antimicrobial properties, like most ant linear peptides (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Molecular Functiontoxin activity
Biological Processenvenomation resulting in modulation of process in another organism
Biological Processmodulation of relaxation of muscle in another organism

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    U10-myrmicitoxin-Mri1a
  • Short names
    U10-MYRTX-Mri1a

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Formicoidea > Formicidae > Myrmicinae > Manica

Accessions

  • Primary accession
    A0A6G9KJK9

Subcellular Location

Keywords

Phenotypes & Variants

Toxic dose

PD50 is 12.12 +-1.5 nmol/g in blowfly (L.caesar) (at 1 hour post-injection).
PD50 is 20.45 +-7.0 nmol/g in blowfly (L.caesar) (at 24 hours post-injection).

PTM/Processing

Features

Showing features for signal, propeptide, peptide, modified residue.

TypeIDPosition(s)Description
Signal1-26
PropeptidePRO_000045305927-52
PeptidePRO_000045306053-81U10-myrmicitoxin-Mri1a
Modified residue81Isoleucine amide

Keywords

Expression

Tissue specificity

Expressed by the venom gland.

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    82
  • Mass (Da)
    8,265
  • Last updated
    2020-08-12 v1
  • Checksum
    BFE34B28BB9A719D
MRLSYISLTIAIIFVMAIVHAPETEAKAYPEADAVAEAIAVGEADAVGVADPGFKSMLAKAALKILKAVAPAAAAAIADKIG

Mass Spectrometry

Molecular mass is 2,850.7 Da. Determined by Electrospray.

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MN765036
EMBL· GenBank· DDBJ
QIQ51446.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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