A0A6C1BW89 · A0A6C1BW89_9AQUI

  • Protein
    CRISPR-associated endoribonuclease Cas2
  • Gene
    cas2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

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MWIILVYDISTENREGQKRLNKVRKIAKRYINHVQKSVFEGNITKSKLERLKSELLQVINKKEDSLIIYIFDDLVDYKREILTEGEDPTSNIL
TypeIDPosition(s)Description
Binding site8Mg2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular FunctionRNA endonuclease activity
Biological Processdefense response to virus
Biological Processmaintenance of CRISPR repeat elements

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    CRISPR-associated endoribonuclease Cas2
  • EC number

Gene names

    • Name
      cas2
    • ORF names
      G3M65_06900

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • T-8
  • Taxonomic lineage
    Bacteria > Aquificota > Aquificia > Aquificales > Aquificaceae > Hydrogenobacter

Accessions

  • Primary accession
    A0A6C1BW89

Proteomes

Interaction

Subunit

Homodimer, forms a heterotetramer with a Cas1 homodimer.

Family & Domains

Sequence similarities

Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    93
  • Mass (Da)
    11,039
  • Last updated
    2020-06-17 v1
  • Checksum
    91B5FC97BE75D2B8
MWIILVYDISTENREGQKRLNKVRKIAKRYINHVQKSVFEGNITKSKLERLKSELLQVINKKEDSLIIYIFDDLVDYKREILTEGEDPTSNIL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP048795
EMBL· GenBank· DDBJ
QID33512.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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