A0A662PK44 · A0A662PK44_UNCTR

  • Protein
    tRNA carboxymethyluridine synthase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

Pathway

tRNA modification.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site82[4Fe-4S] cluster (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet
Binding site87[4Fe-4S] cluster (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet
Binding site90[4Fe-4S] cluster (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionacyltransferase activity
Molecular Functioniron-sulfur cluster binding
Molecular Functionmetal ion binding
Molecular FunctiontRNA binding
Biological ProcesstRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA carboxymethyluridine synthase
  • EC number

Gene names

    • ORF names
      DRN46_00470
      , DRN52_00790

Organism names

Accessions

  • Primary accession
    A0A662PK44

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain65-348Radical SAM core

Sequence similarities

Belongs to the ELP3 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    519
  • Mass (Da)
    60,258
  • Last updated
    2020-04-22 v1
  • Checksum
    211F5BD60D89724A
MLEIIKSIEQGRIKRKEDLHREKIKIARKYKLGRIPSNSEIISFIGEEKVIKEEKYDVLVRKPVRTISGIAVIAVMTSPYPCPHGKCSYCPGGPERGVPQSYTGLEPATMRAIQNEYHPRKQVEHRINQLRKIGHPVEKAEVIIMGGTFTAMPYDYQKWFVKEILDGLTGKTTSSIEEAQKIAEKSEIRNTGLTVETRPDWAKEDQIDRILSLGATRIELGIQSIYEDVLERVNRGHTVEDIVEATRIARDSGFKICYHIMPGLPGSDLKRDYKMFERIFRDSQFKPDMIKIYPCLVIEGTKLYDEWKRGEYTPIRDKEAIELISKVKGELIPKWVRTMRIQRDIPVKAIVDGVKLSNLREVVLKELKKKGKKCNCIRCREVGHKYLKEGRRPKRVEYLIEEYKAGKGKEYFISAEDPEEEILIGYLRLRRVSRKAHREELSGTHVVRELHVYGKSIPIGERKRRWWQHRGVGRRLLEMAEEISMESGKISVLSGIGVREYYYKMGYFKEGPYVSKYLD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QMUK01000002
EMBL· GenBank· DDBJ
RLF91716.1
EMBL· GenBank· DDBJ
Genomic DNA
QMUL01000009
EMBL· GenBank· DDBJ
RLF97217.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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