A0A5Q3A3F5 · A0A5Q3A3F5_9ROSA
- ProteinCytochrome b
- Genecob
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids393 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 heme groups non-covalently.
Note: Binds 2 heme groups non-covalently.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 88 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 102 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 189 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 203 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 208 | a ubiquinone (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | respiratory chain complex III | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity | |
Biological Process | respiratory electron transport chain |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytochrome b
Gene names
Encoded on
- Mitochondrion
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Rosales > Rosaceae > Amygdaloideae > Maleae > Eriobotrya
Accessions
- Primary accessionA0A5Q3A3F5
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 34-58 | Helical | ||||
Sequence: YWWGFGPLAGICLVIQIVTGVFLAM | ||||||
Transmembrane | 83-105 | Helical | ||||
Sequence: LLRYMHANGASMFLIVVHLHIFR | ||||||
Transmembrane | 117-140 | Helical | ||||
Sequence: EFVRCLGVVIFLLMIVTAFTGYVL | ||||||
Transmembrane | 147-171 | Helical | ||||
Sequence: FWGATVITSLASAIPVVGDTIVTWL | ||||||
Transmembrane | 191-210 | Helical | ||||
Sequence: LLPFILVGASLLHLAALHQY | ||||||
Transmembrane | 231-252 | Helical | ||||
Sequence: FYVKDLVGWVAFAIFSSIWIFY | ||||||
Transmembrane | 296-314 | Helical | ||||
Sequence: GGVAAIAPVFICLLALPFF | ||||||
Transmembrane | 326-346 | Helical | ||||
Sequence: PIHQGIFWLLLADCLLLGWIG | ||||||
Transmembrane | 352-371 | Helical | ||||
Sequence: APFVTIGQISPLVFFLFFAI |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-216 | Cytochrome b/b6 N-terminal region profile | ||||
Sequence: MTIRNQRFSLLKQPISSTLNQHLIDYPTPSNLSYWWGFGPLAGICLVIQIVTGVFLAMHHTPHVDLAFNSVEHIMRDVEGGWLLRYMHANGASMFLIVVHLHIFRGLYHASYSSPREFVRCLGVVIFLLMIVTAFTGYVLPWGQMSFWGATVITSLASAIPVVGDTIVTWLWGGFSVDNATLNRFFSLHHLLPFILVGASLLHLAALHQYGSNNPL | ||||||
Domain | 217-387 | Cytochrome b/b6 C-terminal region profile | ||||
Sequence: GVHSEMDKIYFYPYFYVKDLVGWVAFAIFSSIWIFYAPNVLGHPDNYIPANPMPTPPHIVPEWYFLPIHAILRSIPDKSGGVAAIAPVFICLLALPFFKSMYVRSSSFRPIHQGIFWLLLADCLLLGWIGCQPVEAPFVTIGQISPLVFFLFFAITPIPGQVGRGIPNSYT |
Sequence similarities
Belongs to the cytochrome b family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length393
- Mass (Da)44,075
- Last updated2020-02-26 v1
- Checksum58A0F8A071879BCE