A0A5P9QCB9 · A0A5P9QCB9_9MICO

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.
thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Note: Binds 1 thiamine pyrophosphate per subunit.

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.

GO annotations

AspectTerm
Cellular Componentacetolactate synthase complex
Molecular Functionacetolactate synthase activity
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionmagnesium ion binding
Molecular Functionthiamine pyrophosphate binding
Biological Processisoleucine biosynthetic process
Biological Processvaline biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acetolactate synthase
  • EC number

Gene names

    • Name
      ilvB
    • ORF names
      KDY119_02408

Organism names

Accessions

  • Primary accession
    A0A5P9QCB9

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-17Pro residues
Region1-46Disordered
Domain57-172Thiamine pyrophosphate enzyme N-terminal TPP-binding
Domain246-381Thiamine pyrophosphate enzyme central
Domain445-600Thiamine pyrophosphate enzyme TPP-binding

Sequence similarities

Belongs to the TPP enzyme family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    636
  • Mass (Da)
    67,601
  • Last updated
    2020-04-22 v1
  • Checksum
    997BCB3C28DF1406
MVQGPIPAPPRQATPSPVRPSARPATAKPARPAARKVAGEGVGQVADGPRVAPVEVTGAESIVRSLEAVGVDTVFGIPGGAILPLYDPLMDSQKLRHILVRHEQGGGHAASGYAHASGKVGVCMATSGPGATNLVTPIADANIDSIPMVAITGQVAASSIGTDAFQEADIVGITMPVTKHNYLVTDPADIPRTIAEAFHIARTGRPGPVLVDIAKSAMQATTTFSWPQDLDLPGYHPVTKPHSKQIREAAKLLATARKPVLYVGGGVVRADASAELRRLVDLSGAPAVTTLMARGALPDSHPQNLGMPGMHGTVPAVAALQQADLVVALGARFDDRVTGRLDSFAPNAVVVHADIDPAEIGKNRAVDVPIVGDLREVLADLLPELAREQETHGKPDVEAWWQLIDGWRESFPLGYTEPEDGLLAPQYVIERIGAVSGPESVYVGGVGQHQMWAAQFIRYEHPRTWINSGGLGTMGYSVPAAMGAKVARPDATVWAIDGDGCFQMTNQELATCVINEIPIKVAVVNNSSLGMVRQWQTLFYNERYSNTDLHTGHGTRRVPDFVKMADAYGCVGLRCETKADVDATIKRALEIDDQPVVVDFTVSRDAMVWPMVAAGVSNDDIQYARGISPSWDRDDD

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-17Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP045529
EMBL· GenBank· DDBJ
QFU98886.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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