A0A5N6JYS6 · A0A5N6JYS6_MONLA

Function

function

Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendosome membrane
Cellular ComponentESCRT-0 complex
Molecular Functionphosphatidylinositol binding
Molecular Functionubiquitin binding
Biological Processprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Class E vacuolar protein-sorting machinery protein HSE1
  • Alternative names
    • Class E vacuolar protein-sorting machinery protein hse1

Gene names

    • ORF names
      EYC80_009639

Organism names

Accessions

  • Primary accession
    A0A5N6JYS6

Proteomes

Subcellular Location

Endosome membrane
; Peripheral membrane protein

Keywords

  • Cellular component

Interaction

Subunit

Component of the ESCRT-0 complex composed of HSE1 and VPS27.

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain16-144VHS
Region136-158Disordered
Region174-210Disordered
Domain212-271SH3
Region374-733Disordered
Compositional bias398-416Polar residues
Compositional bias418-432Pro residues
Compositional bias460-496Polar residues
Compositional bias507-551Polar residues
Compositional bias561-576Polar residues
Compositional bias577-592Pro residues
Compositional bias593-622Polar residues
Compositional bias623-637Pro residues
Compositional bias649-677Pro residues
Compositional bias678-717Polar residues

Sequence similarities

Belongs to the STAM family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    733
  • Mass (Da)
    81,394
  • Last updated
    2020-04-22 v1
  • Checksum
    EC3DBD7374C70B49
MFRAQQNAFDEVVAKATDENLTSENWEYIMDVCDKVTGEDSGAKDAVASMIKRLAHRNANVQLYTLELANALSQNCGAKIHRELASRAFTDALLRLANDRNTHQQVKAKILERMAEWAGMFKDPDLGIMNDQYHRLKSQNPNLHPPSAPSKSRLTDLDRQKEEEELQMALKLSIQDKSSQPKPAQPSGSSADPAQSPEVVQPQQVPSGTTAATVSRVRALYDFQATDADELQFRKGDIIAVVGSVYKDWWRGSIRGKTGIFPLNYVEKLVDPTPDELQREAQMEAEVFAEIKNVEKLLTLLSTSSSQLDARDNEEITKLYHSTLAIRPKLIELIGKYSQRKDDFTQLNERFIKSCRDYENLLDASMTQAQTYQYGRPGQVPQGPQGYGYPAQAGRPQQEPQRYYTPSQQHEPPYQRQQSPPGGFPPRNGPAPFYVVAPGQQLPQADGRQPYPGQQPPQADGRQPYPSQSPQADGRQPYPGQQPPQSESQQPYPQRDPTPRIASGSKPPPVQYSTQQPQTGHRPQSTYSNPQELATSVYDTPVQQQNPHPYTAYAETDPYTAAPATAQSSQPYNAYKPPQQPSQPPQQPSQPSQPLYEPSAAPSATQPPQQYSAYNPPQQQSQPSEPSFEPPAVPPSTQSPQQYGAYKPPQQPSQPPQPTYEPPAPPSQIPSPVQSSPYPVPEDTRTALPNQGQYKAYQRPDSSDSNQDLSNAPSAPPAEASNPADFYRQNTAY

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias398-416Polar residues
Compositional bias418-432Pro residues
Compositional bias460-496Polar residues
Compositional bias507-551Polar residues
Compositional bias561-576Polar residues
Compositional bias577-592Pro residues
Compositional bias593-622Polar residues
Compositional bias623-637Pro residues
Compositional bias649-677Pro residues
Compositional bias678-717Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VIGI01000011
EMBL· GenBank· DDBJ
KAB8294205.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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