A0A5M6ISH6 · A0A5M6ISH6_9PROT
- ProteinAdenosylcobinamide-GDP ribazoletransferase
- GenecobS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids249 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
Catalytic activity
- adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H+
Cofactor
Pathway
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | adenosylcobinamide-GDP ribazoletransferase activity | |
Molecular Function | cobalamin 5'-phosphate synthase activity | |
Biological Process | cobalamin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAdenosylcobinamide-GDP ribazoletransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Acetobacteraceae > Rhodovastum
Accessions
- Primary accessionA0A5M6ISH6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 65-83 | Helical | ||||
Sequence: APVAAGLAVAVGVLLTGAL | ||||||
Transmembrane | 104-127 | Helical | ||||
Sequence: VLAIMQDSCVGSYGMAGLVVMVGL | ||||||
Transmembrane | 139-164 | Helical | ||||
Sequence: ILPATVLAAQAASRAWAVALMAVLPY | ||||||
Transmembrane | 185-218 | Helical | ||||
Sequence: ALAAATGLAPFLLGVPLPALGAAALVWLGCVLWF |
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length249
- Mass (Da)25,372
- Last updated2020-02-26 v1
- ChecksumA14C401B58263E10
Keywords
- Technical term