A0A5M6ISH6 · A0A5M6ISH6_9PROT

  • Protein
    Adenosylcobinamide-GDP ribazoletransferase
  • Gene
    cobS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionadenosylcobinamide-GDP ribazoletransferase activity
Molecular Functioncobalamin 5'-phosphate synthase activity
Biological Processcobalamin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylcobinamide-GDP ribazoletransferase
  • EC number
  • Alternative names
    • Cobalamin synthase
    • Cobalamin-5'-phosphate synthase

Gene names

    • Name
      cobS
    • ORF names
      F1189_15010

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 21279
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Acetobacteraceae > Rhodovastum

Accessions

  • Primary accession
    A0A5M6ISH6

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane65-83Helical
Transmembrane104-127Helical
Transmembrane139-164Helical
Transmembrane185-218Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the CobS family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    249
  • Mass (Da)
    25,372
  • Last updated
    2020-02-26 v1
  • Checksum
    A14C401B58263E10
MQRLTTEVRAVLAAAVFFSRLPVPRRPLLDAADLRRAACYWPLIGLVVGAAMGTCWAAARPWLAAPVAAGLAVAVGVLLTGALQEDGFADVCDGFGGGATRERVLAIMQDSCVGSYGMAGLVVMVGLRWQAMAALPGAILPATVLAAQAASRAWAVALMAVLPYARGEGSRARPVVGRKSAPRLALAAATGLAPFLLGVPLPALGAAALVWLGCVLWFGGRIGGYTGDCVGATQQVTELAILLAVLATA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VWPK01000022
EMBL· GenBank· DDBJ
KAA5611264.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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