A0A5H9VK07 · A0A5H9VK07_SALET

Function

function

Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO3- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO3- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site80ATP (UniProtKB | ChEBI)
Binding site120ATP (UniProtKB | ChEBI)
Binding site125-131ATP (UniProtKB | ChEBI)
Binding site153-156ATP (UniProtKB | ChEBI)
Binding site161ATP (UniProtKB | ChEBI)
Binding site184ATP (UniProtKB | ChEBI)
Binding site237-238ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function5-(carboxyamino)imidazole ribonucleotide synthase activity
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionphosphoribosylaminoimidazole carboxylase activity
Biological Process'de novo' IMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    N5-carboxyaminoimidazole ribonucleotide synthase
  • EC number
  • Short names
    N5-CAIR synthase
  • Alternative names
    • 5-(carboxyamino)imidazole ribonucleotide synthetase

Gene names

    • Name
      purK
    • ORF names
      GNB81_002338

Organism names

Accessions

  • Primary accession
    A0A5H9VK07

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain84-267ATP-grasp

Sequence similarities

Belongs to the PurK/PurT family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    355
  • Mass (Da)
    39,112
  • Last updated
    2019-12-11 v1
  • Checksum
    80B3051A996F09B2
MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPTAVPVQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLGLATAPWQLLTSADEWSGIFDRLGELAIIKRRVGGYDGRGQWRLRADETGQLPDDCYGECIVERGIHFSGEVSLVGARAHDGSTVFYPLTHNLHQDGILRTSVAFPQANAEQQEQAESMLSAIMQALNYVGVMAMECFITPEGLLINELAPRVHNSGHWTQNGASISQFELHLRAITGLPLPAPVINAPSVMINLIGSELNYDWLKLPLVHLHWYDKAVRPGRKVGHLNLTDSDTSRLSATLEALSPLLPGEYASGIIWAQSKLK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DAATBA010000012
EMBL· GenBank· DDBJ
HAE7852136.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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