A0A5C6CHF5 · A0A5C6CHF5_9BACT

Function

function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site81FMN (UniProtKB | ChEBI)
Active site111Proton donor
Binding site152FMN (UniProtKB | ChEBI)
Binding site185FMN (UniProtKB | ChEBI)
Binding site242-243FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionRNA binding
Molecular FunctiontRNA dihydrouridine synthase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-dihydrouridine synthase
  • EC number

Gene names

    • Name
      dus_1
    • ORF names
      Pla52o_27120

Organism names

  • Taxonomic identifier
  • Strain
    • Pla52o
  • Taxonomic lineage
    Bacteria > Planctomycetota > Planctomycetia > Pirellulales > Pirellulaceae > Novipirellula

Accessions

  • Primary accession
    A0A5C6CHF5

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain24-332DUS-like FMN-binding

Sequence similarities

Belongs to the dus family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    354
  • Mass (Da)
    39,224
  • Last updated
    2019-11-13 v1
  • Checksum
    31011D6ADAB2805B
MTTSFQTRPLTIGNVSIGFPVVQAALSGYSDLPMRVIARRHGASYTVCEVMLDQFLVALSKRQKTKHFLEIDPDEPPVGGQLMGAEPEQFSAGAMKLVEAGFDIIDVNFGCPVKKVLGRCRGGFHLSQPSIAIEILRRTRDIVPDSIPVTVKMRRGMDDTAESRDAFFEILDGAIDAGLAAATVHGRTVKQRYNGPSRWEFLSEVKQHVGDSIKILGSGDLFSAQDCLRMLEQTGIDGVTVARGAIGNPWIFTQAAALAKGDPMPPPPTLHEQASVIQEHVNLCERTYSPERALLLMRKHCIKYSQSHPEHEAVRHDLARVRLREEFDAALERHYGTDGPGRYVPEDYHRKQAE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SJPT01000004
EMBL· GenBank· DDBJ
TWU23177.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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