A0A5B9QFD0 · A0A5B9QFD0_9BACT

  • Protein
    6-phosphogluconate dehydrogenase, decarboxylating
  • Gene
    gndA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.

Features

Showing features for binding site, active site.

147950100150200250300350400450
TypeIDPosition(s)Description
Binding site11-16NADP+ (UniProtKB | ChEBI)
Binding site34-36NADP+ (UniProtKB | ChEBI)
Binding site76-78NADP+ (UniProtKB | ChEBI)
Binding site104NADP+ (UniProtKB | ChEBI)
Binding site104substrate; ligand shared between dimeric partners; in other chain
Binding site130-132substrate; ligand shared between dimeric partners; in other chain
Active site187Proton acceptor
Binding site190-191substrate; ligand shared between dimeric partners; in other chain
Active site194Proton donor
Binding site195substrate; ligand shared between dimeric partners; in other chain
Binding site264substrate; ligand shared between dimeric partners; in other chain
Binding site291substrate; ligand shared between dimeric partners; in other chain
Binding site449substrate; ligand shared between dimeric partners
Binding site455substrate; ligand shared between dimeric partners

GO annotations

AspectTerm
Molecular FunctionNADP binding
Molecular Functionphosphogluconate dehydrogenase (decarboxylating) activity
Biological ProcessD-gluconate metabolic process
Biological Processorganic acid catabolic process
Biological Processpentose-phosphate shunt

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6-phosphogluconate dehydrogenase, decarboxylating
  • EC number

Gene names

    • Name
      gndA
    • ORF names
      Pr1d_39140

Organism names

  • Taxonomic identifier
  • Strain
    • Pr1d
  • Taxonomic lineage
    Bacteria > Planctomycetota > Planctomycetia > Pirellulales > Lacipirellulaceae > Bythopirellula

Accessions

  • Primary accession
    A0A5B9QFD0

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain183-4716-phosphogluconate dehydrogenase C-terminal

Sequence similarities

Belongs to the 6-phosphogluconate dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    479
  • Mass (Da)
    52,870
  • Last updated
    2019-11-13 v1
  • Checksum
    42E567B3571836E5
MSELCDFGLIGLAVMGENLALNVESRGYRVAVFNRTTSKVDDLMAGRAKGKQFVGCHSLEDLVSSLKTPRQVMMMVKAGPAVDDLIETLIPLLSPGDILIDGGNTFYADTERRTKYVESKGLLYCGTGVSGGEEGALLGPSMMPGGSEAAWPHVKPIFQAIAAKVGPNDDIPCCEWVGPRGAGHYVKMVHNGIEYGDMQMICEAYFLLTEGLGLSNEELYDVFEDWYQGELNSYLIEITRDIFSVMDDDGGYLVDKIMDRAGAKGTGKWMSQLALDLGVPSTLVTEAVYARCLSAMKEARVRASKVLSGPNPKYSGDKTNFIEQIRDALYASKICSYAQGFVQMQAAAIEHDWPLNFGDCAMLWRGGCIIRAVFLDRIKEAFDADPKLENLLLAPYFQEAVERSQDGWRHVVASAAQLGIPTPAFSAALAYYDGYRRERLPANLLQAQRDYFGAHTFERLDKPGTFHAEWIQLRKKPKQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP042913
EMBL· GenBank· DDBJ
QEG36599.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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