A0A5B8YY64 · A0A5B8YY64_LEITR
- ProteinPhosphotransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids244 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- D-fructose + ATP = D-fructose 6-phosphate + ADP + H+This reaction proceeds in the forward direction.
Pathway
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.
Carbohydrate metabolism; hexose metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | mitochondrion | |
Molecular Function | ATP binding | |
Molecular Function | D-glucose binding | |
Molecular Function | fructokinase activity | |
Molecular Function | glucokinase activity | |
Biological Process | glucose metabolic process | |
Biological Process | glycolytic process | |
Biological Process | intracellular glucose homeostasis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphotransferase
- EC number
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Leishmaniinae > Leishmania
Accessions
- Primary accessionA0A5B8YY64
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 6-117 | Hexokinase N-terminal | ||||
Sequence: RTDSKFVIPKSALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKGFSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVAR | ||||||
Domain | 126-242 | Hexokinase C-terminal | ||||
Sequence: VGVIIGTGSNACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQRQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHM |
Sequence similarities
Belongs to the hexokinase family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length244
- Mass (Da)26,903
- Last updated2019-11-13 v1
- ChecksumF7F35305311A8E87
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: G | ||||||
Non-terminal residue | 244 | |||||
Sequence: M |