A0A564VYA3 · A0A564VYA3_9BIFI
- ProteinAromatic amino acid transport protein AroP
- GenecycA_1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids512 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Permease that is involved in the active transport across the cytoplasmic membrane of all three aromatic amino acids, phenylalanine, tyrosine and tryptophan.
Catalytic activity
- H+(in) + L-phenylalanine(in) = H+(out) + L-phenylalanine(out)This reaction proceeds in the backward direction.H+ (in)CHEBI:15378
+ L-phenylalanine (in)CHEBI:58095= H+ (out)CHEBI:15378+ L-phenylalanine (out)CHEBI:58095 - H+(in) + L-tryptophan(in) = H+(out) + L-tryptophan(out)This reaction proceeds in the backward direction.
- H+(in) + L-tyrosine(in) = H+(out) + L-tyrosine(out)This reaction proceeds in the backward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Biological Process | amino acid transport | |
Biological Process | transmembrane transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAromatic amino acid transport protein AroP
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Bifidobacteriales > Bifidobacteriaceae > Bifidobacterium
Accessions
- Primary accessionA0A564VYA3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 45-62 | Helical | ||||
Sequence: VQFIAIGGTIGTGLFLGS | ||||||
Transmembrane | 68-87 | Helical | ||||
Sequence: LTGPSIIFVYIGVGLIMFLL | ||||||
Transmembrane | 122-147 | Helical | ||||
Sequence: WTYWIVLILTGMTEITAVSTYFVTFF | ||||||
Transmembrane | 159-180 | Helical | ||||
Sequence: WLIELCFLVALTGINLIAVKVF | ||||||
Transmembrane | 192-212 | Helical | ||||
Sequence: ITLIVGLIVTAIVMLIIGFSY | ||||||
Transmembrane | 245-265 | Helical | ||||
Sequence: WMNFFMSFQMVFFAYQLIEFV | ||||||
Transmembrane | 286-307 | Helical | ||||
Sequence: LIMRILIFYVGALIAIMAIVPW | ||||||
Transmembrane | 333-354 | Helical | ||||
Sequence: WAAALVFFVVITAAASALNSLI | ||||||
Transmembrane | 384-405 | Helical | ||||
Sequence: VPANAIIASGCMILFSPIINAI | ||||||
Transmembrane | 411-434 | Helical | ||||
Sequence: AFVLFASAASAVVIFIYVLTMLAH | ||||||
Transmembrane | 455-472 | Helical | ||||
Sequence: VFDWIAVAFFVLVYVTLF | ||||||
Transmembrane | 478-497 | Helical | ||||
Sequence: IGSAIAGLIWLVTFGGYCLL |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-20 | Disordered | ||||
Sequence: MTFGNTKTEKTGTSTSDATE | ||||||
Domain | 44-478 | Amino acid permease/ SLC12A | ||||
Sequence: HVQFIAIGGTIGTGLFLGSGKSIALTGPSIIFVYIGVGLIMFLLMRAIGEMMYSDPSQHTFINFITRYLGRGWGKFAGWTYWIVLILTGMTEITAVSTYFVTFFGTFGIDLNSWKWLIELCFLVALTGINLIAVKVFGEAEFWFSMIKITLIVGLIVTAIVMLIIGFSYPATHIEGVDGTVSGAAVSLTNITDGFQLAPNGWMNFFMSFQMVFFAYQLIEFVGVTVSETQNPRKVLPKAVNELIMRILIFYVGALIAIMAIVPWRNFHENSDGSFGSPFIMVFKYAGLDWAAALVFFVVITAAASALNSLIYSAGRHLYQLASDSESPAMARLAEVSDHKVPANAIIASGCMILFSPIINAIPGISGAFVLFASAASAVVIFIYVLTMLAHCKYRQSSDFLPDGFVMPAWQVFDWIAVAFFVLVYVTLFLSTDTI |
Sequence similarities
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length512
- Mass (Da)56,267
- Last updated2019-10-16 v1
- Checksum8170734634649699