A0A524M9D4 · A0A524M9D4_9PROT

  • Protein
    3-octaprenyl-4-hydroxybenzoate carboxy-lyase
  • Gene
    ubiD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

prenyl-FMN (UniProtKB | Rhea| CHEBI:87746 )

Note: Binds 1 prenylated FMN (prenyl-FMN) per subunit.

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site172Mn2+ (UniProtKB | ChEBI)
Binding site175-177prenyl-FMN (UniProtKB | ChEBI)
Binding site189-191prenyl-FMN (UniProtKB | ChEBI)
Binding site194-195prenyl-FMN (UniProtKB | ChEBI)
Binding site238Mn2+ (UniProtKB | ChEBI)
Active site287Proton donor

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentplasma membrane
Molecular Function3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Molecular Functionmetal ion binding
Biological Processubiquinone biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-octaprenyl-4-hydroxybenzoate carboxy-lyase
  • EC number
  • Alternative names
    • Polyprenyl p-hydroxybenzoate decarboxylase

Gene names

    • Name
      ubiD
    • ORF names
      E4H07_08630

Organism names

  • Taxonomic identifier
  • Strain
    • Das_tool.concoct.138
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Nitrosomonadales

Accessions

  • Primary accession
    A0A524M9D4

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-893-octaprenyl-4-hydroxybenzoate carboxy-lyase-like N-terminal
Domain124-3223-octaprenyl-4-hydroxybenzoate carboxy-lyase-likw Rift-related
Domain328-4523-octaprenyl-4-hydroxybenzoate carboxy-lyase-like C-terminal

Sequence similarities

Belongs to the UbiD family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    487
  • Mass (Da)
    54,372
  • Last updated
    2019-10-16 v1
  • Checksum
    B2C7C42F6C587BFE
MKYKDLREFLAQLESKGELKRITTVIDPYLEMTEICDRLLKTGGPAVLFENPKGHNIPVLGNLFGTPKRVAMGMGQESVEALREVGKLLAYLKEPDPPKGLKDAWDKLPVLKQVLNMAPKVLTSAPCQDIIWEGKDVDLCKLPIQTCWPGDIGPLITWGLTVTKGPNKTRQNLGIYRQQVIAPNKLIIRWLAHRGGALDFRDFCLASPGQPYPLAVALGADPATILGAVTPVPDSLSEYQFAGLLRGTKTEIIKCLGNDLQVPASAEFVLEGFIYPDETALEGPFGDHTGYYNEQETFPVFTIDRITMRHNPIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFPEITDFYLPPEGCSYRMAVVSMKKQYAGHAKRVMFGVWSFLRQFMYTKFIIVTDDDVNIRDWKEVIWAITTRVDPVRDTLIVENTPIDYLDFASPVSGLGGKMGLDATNKWSGETSRTWGTPIVMDPTVQARIDEIWKDLGI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SPBV01000228
EMBL· GenBank· DDBJ
TFH07789.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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