A0A522MHB9 · A0A522MHB9_9BURK

Function

function

Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homocysteine from O-succinyl-L-homoserine: step 1/1.

GO annotations

AspectTerm
Molecular Functionpyridoxal phosphate binding
Molecular Functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process'de novo' L-methionine biosynthetic process
Biological Processhomocysteine biosynthetic process
Biological Processtranssulfuration

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    O-succinylhomoserine sulfhydrylase
  • EC number
  • Short names
    OSH sulfhydrylase
    ; OSHS sulfhydrylase

Gene names

    • Name
      metZ
    • ORF names
      EPN61_01265

Organism names

  • Taxonomic identifier
  • Strain
    • FW106-02_bin.10
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae

Accessions

  • Primary accession
    A0A522MHB9

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue212N6-(pyridoxal phosphate)lysine

Interaction

Subunit

Homotetramer.

Family & Domains

Sequence similarities

Belongs to the trans-sulfuration enzymes family. MetZ subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    404
  • Mass (Da)
    43,058
  • Last updated
    2019-10-16 v1
  • Checksum
    39522D74BFC0AF96
MTERALPPDLHPETLAVRVAVDKSQYGENSESLYLTSSFIQSDAETAVRRFAGEEEGFTYSRFTNPTVASMEQRLAALEGTEACVGTSSGMAAILLLCMGLLKAGDHVICSQSVFGSTMKLIGGEFGKFGVQTTFVSQTDVAQWRAAIQPNTRLLFAETPTNPLTDVCDIQSLADVAHAAGALLAVDNCFCSPALQQPVKFGADLIIHSGTKYLDGQGRVMAGAVCGPHHLIEEKLVPVLRSAGMTLSAFNAWIVLKGMETLSIRMQAQSTSALALASWLEVQPAIACVHYSGLKSHPQHELAMRQQSGLGGAVVSFDVKGATPEEARRNAFHLIDSTRVCSITANLGDTKTTITHPASTSHGRLTEEQRQAAGIGQGLIRLAVGLEHIDDLKADLARGLDTLP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SCRR01000041
EMBL· GenBank· DDBJ
TAM51808.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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