A0A520W1Z8 · A0A520W1Z8_9ACTN

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site33[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site34[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site99[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site128[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding
Biological Processaerobic respiration
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit B
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit B
    • NDH-1 subunit B

Gene names

    • Name
      nuoB
    • ORF names
      EVA27_00065
      , H2033_00455

Organism names

Accessions

  • Primary accession
    A0A520W1Z8

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain33-141NADH:ubiquinone oxidoreductase-like 20kDa subunit

Sequence similarities

Belongs to the complex I 20 kDa subunit family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    153
  • Mass (Da)
    16,878
  • Last updated
    2019-10-16 v1
  • Checksum
    75F8D7F2C9697B4B
MYTPDNIFTTTIDKAVRWSRTQSMWPVTFGLACCAIEMMAAGSAKYDLARYGMEVFRASPRQADLMIVAGRVSQKMAPVLRQVYDQMADPKWVIAMGACSSTGGMFNNYALVQGVDHIVPVDIYVPGCPPGPQSLMHGILTLHDKIMDGEINR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACERZ010000002
EMBL· GenBank· DDBJ
MBA4811294.1
EMBL· GenBank· DDBJ
Genomic DNA
SGYR01000001
EMBL· GenBank· DDBJ
RZP25490.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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