A0A4Y9RU95 · A0A4Y9RU95_9CAUL
- Protein5-aminolevulinate synthase
- GenehemA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids408 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- succinyl-CoA + glycine + H+ = 5-aminolevulinate + CO2 + CoA
Cofactor
Pathway
Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 5-aminolevulinate synthase activity | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | protoporphyrinogen IX biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name5-aminolevulinate synthase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Caulobacterales > Caulobacteraceae > Brevundimonas
Accessions
- Primary accessionA0A4Y9RU95
Proteomes
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 48-391 | Aminotransferase class I/classII large | ||||
Sequence: DVVIWCSNDYLGMGQHPVVLDAMHDEIDAVGAGAGGTRNISGTTRSAVDLEAELADWHQKEAALLFTSGYVGNEATLSTLQKILPGLITFSDSLNHASMIAGIRHGGGERHVFMHNDLAHLEALLAAAPAEAPKLIAFESVYSMDGDIADLAGTIALAKKYGALTYLDEVHAVGLYGETGAGVAERDGVLDQIDIIECTLGKAIGVMGGYIAADAMIIDAVRSWASGFIFTTSLPPALTAGALASVRHLKAHPELRVQHQERAATLKSRFAAAGIPVMESESHIVPVHVGDPIHCKMISDMLLDEYGVYVQPINYPTVPKGTERLRFTPSPNHTDAMMDHLVQA |
Sequence similarities
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length408
- Mass (Da)44,053
- Last updated2019-09-18 v1
- Checksum9BDE2DF6E93947A6