A0A4Y1Q613 · A0A4Y1Q613_9AGAM
- Proteindeoxyhypusine synthase
- GeneDys1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Catalytic activity
- [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
Pathway
Protein modification; eIF5A hypusination.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | deoxyhypusine synthase activity | |
Biological Process | peptidyl-lysine modification to peptidyl-hypusine |
Keywords
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedeoxyhypusine synthase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Boletales > Boletineae > Boletaceae > Boletoideae > Boletus
Accessions
- Primary accessionA0A4Y1Q613
Subcellular Location
Structure
Sequence
- Sequence statusFragment
- Length62
- Mass (Da)7,200
- Last updated2019-09-18 v1
- Checksum291857484EC17138
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: D | ||||||
Non-terminal residue | 62 | |||||
Sequence: G |