A0A4R2B8U8 · A0A4R2B8U8_9BACI

  • Protein
    Homoserine O-acetyltransferase
  • Gene
    metAA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-acetyl-L-homoserine from L-homoserine: step 1/1.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site111Important for acyl-CoA specificity
Active site142Acyl-thioester intermediate
Binding site163substrate
Binding site192substrate
Site192Important for substrate specificity
Active site235Proton acceptor
Active site237
Binding site249substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionhomoserine O-acetyltransferase activity
Molecular Functionhomoserine O-succinyltransferase activity
Biological ProcessL-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Homoserine O-acetyltransferase
  • EC number
  • Short names
    HAT
  • Alternative names
    • Homoserine transacetylase
      (HTA
      )

Gene names

    • Name
      metAA
    • ORF names
      EV146_109287

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CV53
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Mesobacillus

Accessions

  • Primary accession
    A0A4R2B8U8

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the MetA family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    302
  • Mass (Da)
    35,342
  • Last updated
    2019-07-31 v1
  • Checksum
    01F04B88D1D8FA89
MPIKIPKLLPAREILEEENIFIMDEDRANTQDIRPLNILILNLMPEKEKAEAQFLRLLGNTPLQVNITFLKTATYESKNTSRLHLEQFYTTFEEIRHKKFDGMIITGAPVELIPFDQVDYWGELVKIFEWTKTNVTSTLHICWGAQAALYYHYGVGKYELPQKCSGVYSHRIFDDKEKLLHGFDDVFYAPHSRHTDVSEEAIINSPDLKLLSSSEEAGPFIIHSADRKHIMVTGHLEYETATLAQEYSRDISRGLDVPVPQHYFPDDNPDRKPVNRWRSHANLFFSNWLNYYVYQETPYEWK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SLVV01000009
EMBL· GenBank· DDBJ
TCN23127.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp