A0A4Q4JAV0 · A0A4Q4JAV0_9SPHN
- ProteinAspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
- GenegatC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
Catalytic activity
- L-aspartyl-tRNA(Asn) + L-glutamine + ATP + H2O = L-asparaginyl-tRNA(Asn) + L-glutamate + ADP + phosphate + 2 H+
- L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H+
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity | |
Molecular Function | ATP binding | |
Molecular Function | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity | |
Molecular Function | transferase activity | |
Biological Process | glutaminyl-tRNAGln biosynthesis via transamidation | |
Biological Process | regulation of translational fidelity | |
Biological Process | translation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
- EC number
- Short namesAsp/Glu-ADT subunit C
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingobium
Accessions
- Primary accessionA0A4Q4JAV0
Proteomes
Interaction
Subunit
Heterotrimer of A, B and C subunits.
Structure
Sequence
- Sequence statusComplete
- Length95
- Mass (Da)10,353
- Last updated2019-07-31 v1
- Checksum31787A05ECA49D3B