A0A4D6GY38 · A0A4D6GY38_HALS9

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site9-10ATP (UniProtKB | ChEBI)
Binding site44UMP (UniProtKB | ChEBI)
Binding site45ATP (UniProtKB | ChEBI)
Binding site49ATP (UniProtKB | ChEBI)
Binding site66UMP (UniProtKB | ChEBI)
Binding site114-120UMP (UniProtKB | ChEBI)
Binding site140ATP (UniProtKB | ChEBI)
Binding site146ATP (UniProtKB | ChEBI)
Binding site149ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      APQ99_00441
      , HBSAL_10125

Organism names

Accessions

  • Primary accession
    A0A4D6GY38

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-202Aspartate/glutamate/uridylate kinase

Sequence similarities

Belongs to the UMP kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    241
  • Mass (Da)
    24,898
  • Last updated
    2019-07-03 v1
  • Checksum
    541BC804075FF182
MRVVVSIGGSVLAPGLDADQVDAHADAINELTDAGCEVGAVVGGGGVARDYIGTARELGANEIELDDIGVDVTRLNARLLIAALGGDAAPSPAEDYEDAGEAMRRGDIAVMGGVVAGQTTDAVSAALAEYTDADLLLYATSVPGVFSADPNEDADAEHFTRMTAGELVDIIADIEMNAGSSAPVDLLAAKLIERSGVRTIVLDGTDPRRIVDAVRFGEHDGTDVIPDGTDNQMTYWADNQE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP038631
EMBL· GenBank· DDBJ
QCC45668.1
EMBL· GenBank· DDBJ
Genomic DNA
VRYN01000001
EMBL· GenBank· DDBJ
TYO81928.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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