A0A4D6GY38 · A0A4D6GY38_HALS9
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids241 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- UMP + ATP = UDP + ADP
Activity regulation
Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 9-10 | ATP (UniProtKB | ChEBI) | ||||
Sequence: GS | ||||||
Binding site | 44 | UMP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 45 | ATP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 49 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 66 | UMP (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 114-120 | UMP (UniProtKB | ChEBI) | ||||
Sequence: VVAGQTT | ||||||
Binding site | 140 | ATP (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 146 | ATP (UniProtKB | ChEBI) | ||||
Sequence: F | ||||||
Binding site | 149 | ATP (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | UDP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Halobacteriaceae > Halobacterium
Accessions
- Primary accessionA0A4D6GY38
Proteomes
Subcellular Location
Interaction
Subunit
Homohexamer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-202 | Aspartate/glutamate/uridylate kinase | ||||
Sequence: MRVVVSIGGSVLAPGLDADQVDAHADAINELTDAGCEVGAVVGGGGVARDYIGTARELGANEIELDDIGVDVTRLNARLLIAALGGDAAPSPAEDYEDAGEAMRRGDIAVMGGVVAGQTTDAVSAALAEYTDADLLLYATSVPGVFSADPNEDADAEHFTRMTAGELVDIIADIEMNAGSSAPVDLLAAKLIERSGVRTIVL |
Sequence similarities
Belongs to the UMP kinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length241
- Mass (Da)24,898
- Last updated2019-07-03 v1
- Checksum541BC804075FF182
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP038631 EMBL· GenBank· DDBJ | QCC45668.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
VRYN01000001 EMBL· GenBank· DDBJ | TYO81928.1 EMBL· GenBank· DDBJ | Genomic DNA |