A0A433EFR2 · A0A433EFR2_9MICC

  • Protein
    Elongation factor G
  • Gene
    fusA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

170450100150200250300350400450500550600650700
TypeIDPosition(s)Description
Binding site19-26GTP (UniProtKB | ChEBI)
Binding site83-87GTP (UniProtKB | ChEBI)
Binding site137-140GTP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functiontranslation elongation factor activity
Biological Processribosome disassembly

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Elongation factor G
  • Short names
    EF-G

Gene names

    • Name
      fusA
    • ORF names
      D8M41_00865

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • HSID18069
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Micrococcaceae > Rothia

Accessions

  • Primary accession
    A0A433EFR2

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-290Tr-type G

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    704
  • Mass (Da)
    77,399
  • Last updated
    2019-05-08 v1
  • Checksum
    916B6163FD7FEF59
MAHDVYTDLNKVRNIGIMAHIDAGKTTTTERILFYTGINHKIGETHDGASTMDWMAQEQERGITITSAAITCFWKDNQINIIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSETVWRQADKYDVPRICFVNKMDKMGADFYFTVQTIIDRLGAKPLVLQLPIGAESDFVGVVDLLEMKAYVWPGDSKGDVTMGASYEVQEIPADLQAKAEEYRAEMVEAVAESSEELMEKYLEEGELTVDELKAGIRQLTINGEAFPVLCGSAFKNRGVQPMLDAVIEYLPSPLDVPAVEGSSPSDEEEKLTRKASADEPFAALAYKVAAHPFYGQLIYTRVYSGHAAQGQQVLNSTKGKKERLGKLFQMQSNKENPVEEVTAGHIYAAIGLKDTTTGDTLCDPANPIVLESMTFPAPVIFVAIEPKTKGDQEKMSTAIQKLSAEDPTFTVSLNEETGQTEIGGMGELHLDIIVDRMKREFKVEANVGKPQVAYRETIKKAVEKVDYTHKKQTGGSGQFAKVQVSFEPLPLDGEELYEFEDKVTGGRVPREYIPSVDAGIQDAMKFGILAGYPMVGVKATLIDGAYHDVDSSEMAFKIAGSMVFKEGAKRANPVLLEPLMDVEVRTPEEYMGDVIGDLNSRRGHVRSMEDASGVKIVKALVPLTEMFGYIGDLRGKTQGRAVFSMAFDSYGEVPKNVADEIIQKSRGE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RBMG01000001
EMBL· GenBank· DDBJ
RUP72972.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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