A0A430UNW7 · A0A430UNW7_THESC

  • Protein
    Endonuclease MutS2
  • Gene
    mutS2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

1746100200300400500600700
TypeIDPosition(s)Description
Binding site315-322ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionendonuclease activity
Molecular Functionmismatched DNA binding
Biological Processmismatch repair
Biological Processnegative regulation of DNA recombination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Endonuclease MutS2
  • EC number

Gene names

    • Name
      mutS2
    • ORF names
      CSW30_07700

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 17_S17
  • Taxonomic lineage
    Bacteria > Deinococcota > Deinococci > Thermales > Thermaceae > Thermus

Accessions

  • Primary accession
    A0A430UNW7

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for coiled coil, domain.

TypeIDPosition(s)Description
Coiled coil215-246
Coiled coil494-578
Domain670-745Smr

Sequence similarities

Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    746
  • Mass (Da)
    82,531
  • Last updated
    2019-05-08 v1
  • Checksum
    655247A86A706DFF
MRDVLEVLEFPKVRALLAERAKTPLGRRLALALVPLSQEEAERRHQLTQEALAYPYTLPEAGTLEEAYQKAQGGARLSGLELLKGAQALEEAMALKEELLPLQSLLSQVAAGIGDHGAFLAKVRKALDEEGAVRDEASPKLFAIRRELKPLRQQILDKLYALMDRHPEAIQDRFVTLRRERYCIPVRAGMAQRIPGLLLDESESGATLFIEPLSVVKLNNRLQALRLQEEEEVNRILRELSEALAADEELSGTLKALSLLDLVQAQAALARDFGLSRPRFGEAYELFQAFHPLIPNPVPNSLALDGERRLILISGPNMGGKTALLKTLGLAVLMAQSGLFVAAKKATLAWPDRVFADIGDEQSLQENLSTFAGHLRRLKEMLESATAQSLVLIDELGSGTDPEEGAALSQAILEALLEKGVKGLVTTHLSPLKAFAQGRTGIQNASMRFDLEDLRPTYELVLGVPGRSYALAIARRLSLPEAVLKRAESLLPQGGRLEALLEELEAERLRLEEERSQLLSQMAQVEALRKRLVEREARFEEERQERLKALEEEIRQKLLKVEAELKSLKEKAKTQGKKDALRELLALRERYARATPKGAWEVPRGLEAGQMVEIPSLRRQGRLLELRGEEALVQVGPVKMTVKAKELTPLKAQETPKAIGLKPRREVKEVDLRGLTVEEALLEVASALEEARALGLPTLRLLHGKGTGALRQAIREALRRDKRVETFADAPPHEGGHGVTVVVLKG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PEMG01000222
EMBL· GenBank· DDBJ
RTI08026.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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