A0A3M6K4Y7 · A0A3M6K4Y7_9ARCH

Function

function

Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Molecular FunctionDNA binding
Molecular FunctionDNA-directed DNA polymerase activity
Molecular Functionsingle-stranded DNA 3'-5' DNA exonuclease activity
Biological ProcessDNA catabolic process
Biological ProcessDNA-templated DNA replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA polymerase II large subunit
  • EC number
  • Short names
    Pol II
  • Alternative names
    • Exodeoxyribonuclease large subunit
      (EC:3.1.11.1
      ) . EC:3.1.11.1 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      polC
    • ORF names
      EA437_00705

Organism names

  • Taxonomic identifier
  • Strain
    • GoM_MAG2
  • Taxonomic lineage
    Archaea > Nitrososphaerota > Nitrososphaeria > Nitrosopumilales > Nitrosopumilaceae > Candidatus Nitrosomarinus

Accessions

  • Primary accession
    A0A3M6K4Y7

Proteomes

Interaction

Subunit

Heterodimer of a large subunit and a small subunit.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain21-876DNA polymerase II large subunit DP2 N-terminal

Sequence similarities

Belongs to the archaeal DNA polymerase II family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,125
  • Mass (Da)
    126,166
  • Last updated
    2019-02-13 v1
  • Checksum
    58D52EFECD8A9D71
MSENDAISRIRGIEMPDYYLNYYSNLSKETYSIFEHAALAKSTLVDSSGIIEPKIAFDLADRVAKMHEIDIAEPLREILKINGKELSALILAKDIALGKYSLPEAPLEEKLDLAVRVGLAIITEGVTIAPLQGISEVKIKKNKDGTDYLSVSIAGPMRSAGGTESAVTLLIADHVRKIAGLSKFQANSFDDETGRFVEELRIYEREASSFQFHILDEDIEHVISNLPVELAGVDTDPFEVVNHKGMTRIQTDRVRGGALRVLNDGLIGRSKKLLKRIEMYNLDGWEWLNDLKGAVQTGDNQEDAAAKRMREVITGRSVLSMPNKLGGFRLRYGRACNTGFAAVGFHPVVAEILDHTIAVGTQVKIDIPGKGATVAFVDTIETPTVRLQNGDVVKIKDVKHGIEIKNKIEKILHLGDVLITFGDFLENNAQLVPSGYVEEIWIEQLKEIISKSEAKNPFLEQFLIKTPSVDEALKISLDYNFSLHPHYLYYWDKISLEELDQLLQAKNVNENKIEYSTEKKKILEKLGTPHKVENQSIILENEEAKIFFNLLFLTKPEINDLSIPEILSISSKIKINNKFSTSIGVRIGRPEKAAPRQMKPPTHTLFPISDKGGPTRDLLKASRNEHFFANIHNRFCEQCNEPSIGINCSNCGKKTSVIFRCNNCRDTLTEPFCEKCKRKAPAHSHKEFPLKSRLLLAQEKMGLRAKEPFKGLKELISQDKIAEPLEKGLVRQTFGLTTFKDGTIRFDATNSPLTQFKPSWIGTSIEKLKELGYSHDIDGKPLENIDQIIELRMQDVVIPEESGKYLVSTCKYIDTLLTKFYGKSSFYNVNNPEELIGHLIIGLAPHTSVGIVGRVIGYTDTHVCFGTPNWHSAKRRDADGDADSIMLLMDSLLNFSRQFLSDRIGGLMDAPLLVQPLVLPHESQPQAHNLEVTKIFPLEFFESTIQQSKASDVTSVEIIKSRLETKRQFFDYHFTHFTSSLTTSKSRSAYSTLGSMLDKFDMQVKNAELINVVNPSELVSNVISTHLVPDIMGNLRAYARQSFRCTACGKSYRRMPLIQTCVCGHKLIATITRGSVEKYLKLAKRLVDKYDVGEYQRGRIHALSDEIELVFGKGQGDQSLLTDYA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
REGF01000003
EMBL· GenBank· DDBJ
RMW36622.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp