A0A3D3HQQ6 · A0A3D3HQQ6_9GAMM

Function

function

Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Function[formate-C-acetyltransferase]-activating enzyme activity
Molecular Functionlyase activity
Molecular Functionmetal ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate formate-lyase-activating enzyme
  • EC number

Gene names

    • Name
      pflA
    • ORF names
      DIT05_14895

Organism names

Accessions

  • Primary accession
    A0A3D3HQQ6

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain16-239Radical SAM core

Sequence similarities

Belongs to the organic radical-activating enzymes family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    246
  • Mass (Da)
    28,279
  • Last updated
    2019-01-16 v1
  • Checksum
    798AF7725BB46217
MSVLGRIHSFESCGTVDGPGIRFIIFFQGCLMRCLYCHNRDTWDLHGGQEVTVDELMKEATTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKEGIHTCLDTNGFVRRYDPVIDELMEVTDLVMLDLKQLDDSIHQNLVGVSNHRTLQFARYLAERNQKTWIRYVVVPGWSDDEHSAHLLGDFTKDMKNIEKIELLPYHELGKHKWTAMNEEYKLDGVNPPSKETMEKVKSILESYGHKVMY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQAE01000030
EMBL· GenBank· DDBJ
HCM63810.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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