A0A399RC56 · A0A399RC56_9PROT

  • Protein
    Methionine--tRNA ligase
  • Gene
    metG
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site148Zn2+ (UniProtKB | ChEBI)
Binding site151Zn2+ (UniProtKB | ChEBI)
Binding site161Zn2+ (UniProtKB | ChEBI)
Binding site164Zn2+ (UniProtKB | ChEBI)
Binding site352ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentaminoacyl-tRNA synthetase multienzyme complex
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionmethionine-tRNA ligase activity
Biological Processmethionyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methionine--tRNA ligase
  • EC number
  • Alternative names
    • Methionyl-tRNA synthetase
      (MetRS
      )

Gene names

    • Name
      metG
    • ORF names
      D1222_12280

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CCUG67844
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomonadales > Hyphomonadaceae > Henriciella

Accessions

  • Primary accession
    A0A399RC56

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain, motif.

TypeIDPosition(s)Description
Domain9-412Methionyl/Leucyl tRNA synthetase
Motif16-26'HIGH' region
Motif349-353'KMSKS' region
Domain424-579Methionyl-tRNA synthetase anticodon-binding

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    580
  • Mass (Da)
    65,334
  • Last updated
    2018-12-05 v1
  • Checksum
    32BFA8BAFC705FA1
MTKSAPRRILVTSALPYINGVKHLGNLAGSMLPADVYSRFQRLRGHDVLYICATDEHGTPAELAAQAANVPVRQYVDEQHEIQKKAGEDFLLSYDHFGRSCSEENAALTQHFAHVLEANGLIEERTMRQVYSIDDERFLPDRYVEGTCPHCEFEKARGDQCDNCGRLLDPVDLINPYSAVSGSRNVEVRETRHLFLLQSQMQERIQAWIEASTDWPPLARSIALKWLDEGLRDRAITRDLSWGVPVTNPDGSIREGFETKVFYVWFDAPIEYIAATEEWAKAKGEPEAWRRWWRTDEGADKVDYVQFMGKDNVAFHTVGFPVTILGSQEPWKLVDRLKAFNWVTWYGGKFSTSNKRGVFMDQALDLLPADYWRWYLTANAPEGSDAAFTWEGFQSSINSDLANVLGNFVNRITKYCASKFDGKVPEGGEAGEAESWMVAELETRLPQLVQHYENMDFRKAAAETRAIWAAGNEYLTKAEPWVKYKNDVDAAAVGVRAGLNLAALFGIIAQPIIPEAAAMILDALGAPEDRRTLSEEAFADIPALLDALPRGHEISPPDVLFRKIEDDQVAEWTERFGGES

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QWGA01000007
EMBL· GenBank· DDBJ
RIJ29126.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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