A0A380G6F0 · A0A380G6F0_STAIN

Function

function

Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site268[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site271[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site303[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site310[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Function4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)
Molecular Function4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)
Molecular Functioniron ion binding
Biological Processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
Biological Processterpenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
  • EC number
  • Alternative names
    • 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase

Gene names

    • Name
      ispG
    • ORF names
      NCTC11048_01696

Organism names

Accessions

  • Primary accession
    A0A380G6F0

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the IspG family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    368
  • Mass (Da)
    39,645
  • Last updated
    2018-11-07 v1
  • Checksum
    D6310A5AF2C0A1C2
MAEITHRKNTRPVKVGDLTIGGADEVVIQSMTTTKTHDVEATVAEIKRLEEAGCQIVRVACPNEEDAHAIKDIKAQINIPLVVDIHFNYKLALIAIENGADKIRINPGNIGRREKVEAVVEACKAKGIPIRIGVNAGSLEKHILKKYGYPTADGMVESALHHIKILEELDFHDIIVSMKASDVNLAIEAYTKAAKAFDYPLHLGITESGTLFNGTVKSSAGLGAILSLGIGNTMRISLSADPVEEVKVAKSLLKSFGLASNAATLIACPTCGRIEIDLISIANEVEEYIEKLQIPLKVAVLGCAVNGPGEAREADIGIAGARGEGLLFMKGKTVRKVPEETMVDELKMEIDKLAAEWEENKKQEAAQN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
UHDP01000003
EMBL· GenBank· DDBJ
SUM46635.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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