A0A347AJY2 · A0A347AJY2_9EURY
- ProteinHomoserine O-acetyltransferase
- GenemetXA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids493 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
Catalytic activity
- L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-acetyl-L-homoserine from L-homoserine: step 1/1.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 152 | Nucleophile | ||||
Sequence: S | ||||||
Binding site | 221 | substrate | ||||
Sequence: R | ||||||
Active site | 317 | |||||
Sequence: D | ||||||
Active site | 350 | |||||
Sequence: H | ||||||
Binding site | 351 | substrate | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | homoserine O-acetyltransferase activity | |
Biological Process | homoserine metabolic process | |
Biological Process | methionine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHomoserine O-acetyltransferase
- EC number
- Short namesHAT
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Methanomada group > Methanobacteria > Methanobacteriales > Methanobacteriaceae > Methanobacterium
Accessions
- Primary accessionA0A347AJY2
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 377-434 | CBS | ||||
Sequence: MTLNAATITEDSSIEEAAELMLDEKVTHLPVVSEDRRMLGIVTAWDISKAVALKYDKL | ||||||
Domain | 438-493 | CBS | ||||
Sequence: MTRDVVTALPQDPIELAARKMRKHNISSLPVVNDHGNVLGLITTDHISTLIAGDKY |
Sequence similarities
Belongs to the AB hydrolase superfamily. MetX family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length493
- Mass (Da)54,879
- Last updated2018-11-07 v1
- ChecksumBD52E09E063A6334
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP022706 EMBL· GenBank· DDBJ | AXV39279.1 EMBL· GenBank· DDBJ | Genomic DNA |