A0A327R0R7 · A0A327R0R7_9FLAO

  • Protein
    UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  • Gene
    murF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site97-103ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Molecular FunctionUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
Biological Processcell division
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  • EC number
  • Alternative names
    • D-alanyl-D-alanine-adding enzyme

Gene names

    • Name
      murF
    • ORF names
      LV92_02959

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 23522
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Arenibacter

Accessions

  • Primary accession
    A0A327R0R7

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain16-73Mur ligase N-terminal catalytic
Domain96-275Mur ligase central
Domain299-379Mur ligase C-terminal

Sequence similarities

Belongs to the MurCDEF family. MurF subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    424
  • Mass (Da)
    47,267
  • Last updated
    2018-10-10 v1
  • Checksum
    EA81C95F90D6481D
MTIEQLHQLFLGFPQVCTDTRKISPNCIFFALKGDNFNGNFYAGQALDQGASYAVVDEEEYAVGDKTILVKNVLTTLQNLSQFHRNFCKAKVIGLTGSNGKTTTKELITAVLSRKYKTIATKGNLNNHIGVPLTLLSITPDTEMAIVEMGANHLKEIEFLCKLAGPDFGYITNFGKAHLEGFGSEAGVIKGKSELYDFLTSHDKSVFFNADDPIQKEKLATVIKKFGYSQNDSEFFQIKLIGADPFVKIAVDNIHITTQLVGSYNFTNCCAAILIGRYFNVELDEIKKGIENYIPQNNRSQIIDKNGHHIILDAYNANPTSMKAALENFQQIKADYKIAFLGDMFELGKTAEKEHQEISNIAANMNFDQVFLIGENFFKTKSDSSKFKSFDHLKETLNNKTLKSATILVKGSRGMALERILELL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QLLN01000005
EMBL· GenBank· DDBJ
RAJ10211.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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