A0A2W5B5R0 · A0A2W5B5R0_9CORY

Function

function

Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

154350100150200250300350400450500
TypeIDPosition(s)Description
Binding site92-96GTP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functiontranslation release factor activity, codon nonspecific
Molecular Functiontranslation release factor activity, codon specific
Biological Processregulation of translational termination

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Peptide chain release factor 3
  • Short names
    RF-3

Gene names

    • Name
      prfC
    • ORF names
      DI609_05790

Organism names

  • Taxonomic identifier
  • Strain
    • S2_012_000_R3_87
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium

Accessions

  • Primary accession
    A0A2W5B5R0

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-285Tr-type G

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    543
  • Mass (Da)
    59,428
  • Last updated
    2018-09-12 v1
  • Checksum
    5A7CDDF170012CF2
MSIASEASRRRTFAVIAHPDAGKSTLTEALALHAHVINEAGAVHGKGNRKSTVSDWMEMEKDRGISVASSALQFEYAPEGHEGEPYMINLVDTPGHADFSEDTYRVLTAVDAAVMLIDAAKGLEPQTLKLFRVCKARGLPIITVINKWDRAGREPLELVDEIVNEIQLQPTPLYWPVGIAGDFRGLAHINDDGEADEYVHFLRTAGGSTIAPEEHYAPAAAADKEEDAWETAVEEAELLAADGALHDQELFEQCVTSPLIFASAMLNFGVHQILDTLCAIAPQPHSRESDPKAIEAATSAIDETREVTDEFSGVIFKVQAGMDRKHRDNLAFMRVVSGEFERGMQVSHAQSGRSFSTKYALTVFGRTRDTVESAYPGDIVGLVNAGSLAPGDTIYTGKKVQFKPMPQFAPEAFRILRAKSLGDYKAFRKGLDQLAAEGVVQILRNDTRGDAAPVMAAVGPMQFEVMQARMEVEYNVETVTEPIPYSVARRTDAESAPELGRQRGVEIFTRSDGELIALFGDKWKLAFVEKEHPELTIDTLVAD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QFNY01000114
EMBL· GenBank· DDBJ
PZP00717.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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