A0A2U8GKL6 · A0A2U8GKL6_9RHOO

  • Protein
    Carbamoyltransferase HypF
  • Gene
    hypF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

Catalytic activity

Pathway

Protein modification; [NiFe] hydrogenase maturation.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site27
Active site45

GO annotations

AspectTerm
Molecular Functionacylphosphatase activity
Molecular Functioncarboxyl- or carbamoyltransferase activity
Molecular Functiondouble-stranded RNA binding
Molecular Functionligase activity
Molecular Functionzinc ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Carbamoyltransferase HypF
  • EC number

Gene names

    • Name
      hypF
    • ORF names
      CEW83_00750

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • TSPY31
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Rhodocyclales > Zoogloeaceae > Parazoarcus

Accessions

  • Primary accession
    A0A2U8GKL6

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain12-99Acylphosphatase-like
Domain208-415YrdC-like

Sequence similarities

Belongs to the carbamoyltransferase HypF family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    786
  • Mass (Da)
    84,654
  • Last updated
    2018-09-12 v1
  • Checksum
    B2D969FB96ADE76E
MAQDFSQPRLERRHIRVRGVVQGVGFRPFVYRLAQTLDLSGWVRNDGDGVELEGQGLPGNLSALIARIRSEAPSLARVDSIHTRLCDADPADQGFTIRTSESGAVSTTIGHDSAVCADCLAELFDPADRRWRYPFINCTHCGPRYTITRALPYDRSNTSMATFAQCPACQREYDAPVHRRFHAEPNACADCGPQLSLLEAAGVRVATRDPIADTLLRLLTGEIVAIKGLGGFHLVCDARNPEAVERLRARKGRGGKPFAVMVANLASARRWARLASAEEALLAGAERPVVLCEKRPSVDNELWGLAPDLGSIGLMLPYTPLHYLLFHDNAGRPSGTDWLGEVQDLALVMTSANPGGEPLVTDNQEALQRLKGIADAYLMHDRDILSRCDDSVMVAERSALAGARETPRFVRRARGFTPRSIRLAQKGVPVLAFGAWLKNAVCLTRGDEAFLSEHIGDLDNPGVCVAMDQAAEHLQRILAIQPEAVAHDLHPDFHSTRAALALADRLGVPAIGVQHHHAHIAAVLAEHRRSGPVLGVALDGVGLGSDGSAWGGELLTVDGAAFERVGHLAPLALPGGDQAARAPWRMAASALHRMGRGADIAPRFATQRGAAQIKVLLDKPHLCPTTTSMGRWFDAAAGLLGVCERMDYDAEAAMRLESLAASYGSALRAHRGWAVREDESGAELDLLPLLAELARERNPARGAAVFHATLLAALEDWIVAAARHERLSTVALGGGCFLNRQLAFELPRRLSARGLEVLTARQAPCNDGGIALGQAWVAIQQLQPGN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP022187
EMBL· GenBank· DDBJ
AWI73930.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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