A0A2T8MF55 · A0A2T8MF55_SALAN
- ProteinUDP-N-acetylglucosamine 1-carboxyvinyltransferase
- GenemurA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids419 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
Catalytic activity
- phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine + phosphate
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 22-23 | phosphoenolpyruvate (UniProtKB | ChEBI) | ||||
Sequence: KN | ||||||
Binding site | 91 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Active site | 115 | Proton donor | ||||
Sequence: C | ||||||
Binding site | 120-124 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | ||||
Sequence: RPVDL | ||||||
Binding site | 160-163 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | ||||
Sequence: KVSV | ||||||
Binding site | 305 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 327 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | ||||
Sequence: V |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape | |
Biological Process | UDP-N-acetylgalactosamine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylglucosamine 1-carboxyvinyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionA0A2T8MF55
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 115 | 2-(S-cysteinyl)pyruvic acid O-phosphothioketal | ||||
Sequence: C |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 6-406 | Enolpyruvate transferase | ||||
Sequence: VQGPTTLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDASQVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHITGLEQLGATIKLEEGYVKASVEGRLKGAHIVMDKVSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLVTLGAKIAGQGTDRITIEGVERLGGGVYRVLPDRIETGTFLVAAAISRGKILCRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGARAEIESNTVICHGVETLSGAQVMATDLRASASLVLAGCIAEGTTIVDRIYHIDRGYERIEDKL |
Sequence similarities
Belongs to the EPSP synthase family. MurA subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length419
- Mass (Da)44,741
- Last updated2018-09-12 v1
- ChecksumCA147092EC0F61AC
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAFZFQ010000009 EMBL· GenBank· DDBJ | EBL4823349.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHFSU010000011 EMBL· GenBank· DDBJ | EBV5960530.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHFTY010000002 EMBL· GenBank· DDBJ | EBV6100450.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHLLN010000015 EMBL· GenBank· DDBJ | EBX5017349.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHPVZ010000003 EMBL· GenBank· DDBJ | EBZ0397828.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHUUN010000018 EMBL· GenBank· DDBJ | ECA5741009.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHVYN010000014 EMBL· GenBank· DDBJ | ECA9357374.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHZBB010000010 EMBL· GenBank· DDBJ | ECB8975382.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKJAJ010000016 EMBL· GenBank· DDBJ | ECS2639470.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKJCB010000006 EMBL· GenBank· DDBJ | ECS2826681.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKKDH010000010 EMBL· GenBank· DDBJ | ECS6136503.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKLVW010000004 EMBL· GenBank· DDBJ | ECT1476202.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKMPV010000008 EMBL· GenBank· DDBJ | ECT3923762.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKOYA010000007 EMBL· GenBank· DDBJ | ECU1186535.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKQAO010000011 EMBL· GenBank· DDBJ | ECU4735849.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKRBH010000003 EMBL· GenBank· DDBJ | ECU7855417.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKSYA010000005 EMBL· GenBank· DDBJ | ECV0338133.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKSWZ010000011 EMBL· GenBank· DDBJ | ECV0504176.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAGON010000006 EMBL· GenBank· DDBJ | HAB3942383.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASBR010000005 EMBL· GenBank· DDBJ | HAE4847345.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAATFV010000018 EMBL· GenBank· DDBJ | HAE8375035.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
VCUW02000001 EMBL· GenBank· DDBJ | TRG52859.1 EMBL· GenBank· DDBJ | Genomic DNA |