A0A2T5XY18 · A0A2T5XY18_9FLAO

Function

function

Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion.

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.
Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site50Zn2+ (UniProtKB | ChEBI); catalytic
Active site52Proton donor
Binding site77Zn2+ (UniProtKB | ChEBI); catalytic
Binding site86Zn2+ (UniProtKB | ChEBI); catalytic
Binding site156NADP+ (UniProtKB | ChEBI)
Binding site175NADP+ (UniProtKB | ChEBI)
Binding site189substrate
Binding site201NADP+ (UniProtKB | ChEBI)
Binding site205NADP+ (UniProtKB | ChEBI)
Binding site209substrate
Binding site212substrate
Binding site291substrate

GO annotations

AspectTerm
Molecular Function5-amino-6-(5-phosphoribosylamino)uracil reductase activity
Molecular Functiondiaminohydroxyphosphoribosylaminopyrimidine deaminase activity
Molecular Functionzinc ion binding
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Riboflavin biosynthesis protein RibD

Including 2 domains:

  • Recommended name
    Diaminohydroxyphosphoribosylaminopyrimidine deaminase
  • EC number
  • Short names
    DRAP deaminase
  • Alternative names
    • Riboflavin-specific deaminase
  • Recommended name
    5-amino-6-(5-phosphoribosylamino)uracil reductase
  • EC number
  • Alternative names
    • HTP reductase

Gene names

    • ORF names
      C8P65_10182

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 22902
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Capnocytophaga

Accessions

  • Primary accession
    A0A2T5XY18

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-125CMP/dCMP-type deaminase

Sequence similarities

In the C-terminal section; belongs to the HTP reductase family.
In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    350
  • Mass (Da)
    39,328
  • Last updated
    2018-07-18 v1
  • Checksum
    4D22C58BDB4C1C54
MTDQQYIHRCIQLAQNGLGTTYPNPVVGSVIVYKDRVIGEGWHVRAGEAHAEVRAIASVKDKQLLSQSTLYVSLEPCSHYGKTPPCADLIIAHRIPRVVIGCTDPFAKVAGRGIQKLREAGCEVVVGVCQEECEALNKRFFTFHQKKRPYIFLKWAETRDGLIAPLHKQERAPQWITGAYARQYVHLLRSTEAAILVGAGTVWADNPSLSTRSWYGKSPLRVIIDPRLSTRKDFNVWNDEVPTLFIADRDYKGVRHFGQRTEVACIDFGGEVLPQLCKVLYEREVQSLIVEGGAHTLQQFIKADLWDEALVFRGDTVFTNGLKAPQLSHACLHSVESFPPDFLMTMVNNK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QBKG01000001
EMBL· GenBank· DDBJ
PTX08418.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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