A0A2S4XYK5 · A0A2S4XYK5_9ACTN

  • Protein
    Fumarate hydratase class I
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the reversible hydration of fumarate to (S)-malate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.

GO annotations

AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionfumarate hydratase activity
Molecular Functionmetal ion binding
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fumarate hydratase class I
  • EC number

Gene names

    • ORF names
      C3486_08410

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Ru73
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0A2S4XYK5

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain56-332Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Domain338-549Fe-S hydro-lyase tartrate dehydratase beta-type catalytic

Sequence similarities

Belongs to the class-I fumarase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    564
  • Mass (Da)
    61,312
  • Last updated
    2018-07-18 v1
  • Checksum
    1A8DD03F242CF59A
MSVSSRPALPAFAYTDLLPTGEDKTPYRLITKEGVSTFEADGRTFLKVEPEALRKLAEAAIHDIQHYLRPEHLGQLRKIIDDPEASANDKFVALDLLKNANIAAAGVLPMCQDTGTAIVMGKRGQNVLTQGGDEEALSRGIYDAYTNLNLRYSQMAPLTMWDEKNTGSNLPAQIELYATDGDAYKFLFMAKGGGSANKSFLFQETKAVLNEASMMKFLEQKIRSLGTAACPPYHLAIVVGGTSAEYALKTAKYASAHYLDELPEEGSPTGHGFRDKELEEKVFELTQKIGIGAQFGGKYFCHDVRVVRLPRHGASCPVAIAVSCSADRQAVAKITAEGVFLEQLETDPARFLPDTTDEELTEGAGADLDAVKIDLNQPMDDILAELTKHPVKTRLSLTGTLVVARDIAHAKIKERLDAGEEMPEYLKNHPVYYAGPAKTPEGYASGSFGPTTAGRMDAYVEQFQAAGGSKVMLAKGNRSQQVTEACHAHGGFYLGSIGGPAARLAQDCIKKVEVLEYEELGMEAVWKIEVEDFPAFIVVDDKGNDFFQDPAPVPTFTSIPVRTS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PQSQ01000012
EMBL· GenBank· DDBJ
POX41694.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp