A0A2S4XYK5 · A0A2S4XYK5_9ACTN
- ProteinFumarate hydratase class I
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids564 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the reversible hydration of fumarate to (S)-malate.
Catalytic activity
- (S)-malate = fumarate + H2O
Cofactor
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | fumarate hydratase activity | |
Molecular Function | metal ion binding | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFumarate hydratase class I
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces
Accessions
- Primary accessionA0A2S4XYK5
Proteomes
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 56-332 | Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic | ||||
Sequence: LAEAAIHDIQHYLRPEHLGQLRKIIDDPEASANDKFVALDLLKNANIAAAGVLPMCQDTGTAIVMGKRGQNVLTQGGDEEALSRGIYDAYTNLNLRYSQMAPLTMWDEKNTGSNLPAQIELYATDGDAYKFLFMAKGGGSANKSFLFQETKAVLNEASMMKFLEQKIRSLGTAACPPYHLAIVVGGTSAEYALKTAKYASAHYLDELPEEGSPTGHGFRDKELEEKVFELTQKIGIGAQFGGKYFCHDVRVVRLPRHGASCPVAIAVSCSADRQAVA | ||||||
Domain | 338-549 | Fe-S hydro-lyase tartrate dehydratase beta-type catalytic | ||||
Sequence: GVFLEQLETDPARFLPDTTDEELTEGAGADLDAVKIDLNQPMDDILAELTKHPVKTRLSLTGTLVVARDIAHAKIKERLDAGEEMPEYLKNHPVYYAGPAKTPEGYASGSFGPTTAGRMDAYVEQFQAAGGSKVMLAKGNRSQQVTEACHAHGGFYLGSIGGPAARLAQDCIKKVEVLEYEELGMEAVWKIEVEDFPAFIVVDDKGNDFFQD |
Sequence similarities
Belongs to the class-I fumarase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length564
- Mass (Da)61,312
- Last updated2018-07-18 v1
- Checksum1A8DD03F242CF59A
Keywords
- Technical term