A0A2H6ATW0 · A0A2H6ATW0_UNCXX

  • Protein
    Homoserine O-acetyltransferase
  • Gene
    metA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-acetyl-L-homoserine from L-homoserine: step 1/1.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site111Important for acyl-CoA specificity
Active site142Acyl-thioester intermediate
Binding site163substrate
Binding site196substrate
Site196Important for substrate specificity
Active site239Proton acceptor
Active site241
Binding site253substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionhomoserine O-acetyltransferase activity
Molecular Functionhomoserine O-succinyltransferase activity
Biological ProcessL-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Homoserine O-acetyltransferase
  • EC number
  • Short names
    HAT
  • Alternative names
    • Homoserine transacetylase
      (HTA
      )

Gene names

    • Name
      metA
    • Synonyms
      metAA
    • ORF names
      HRbin39_00748

Organism names

Accessions

  • Primary accession
    A0A2H6ATW0

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the MetA family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    320
  • Mass (Da)
    37,174
  • Last updated
    2018-02-28 v1
  • Checksum
    AFAD44F65DB38EC7
MPIKIPSDLPAAAKLADEGVRVIGEEEALRQDIRPMEIALLNLMPEKPRTEVQLARLLGATPLQVELTLLTTSTYQPRTVPLSHLQRFYRTWEDVRHRKFDGLIVTGAPVELLPFEEVKYWKELCAILDWSRTHVHSSFFICWGAQAALYHFHGVPKHTLPCKRFGIYTHYVVEREDARRNPLVRGFDDYFLVPVSRHTETRIEDLPQDAGLEVLAVSNAAGLCLLYEPKYRAVYMFNHLEYDTDTLHNEYMRDRAKRPDVFMPINYYPDDDPSKPPRNCWRAYAHLLFANWINEMYQTTPYAIERIGEDRVEARTTAAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BEIP01000089
EMBL· GenBank· DDBJ
GBD41367.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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