A0A2G9FPJ1 · A0A2G9FPJ1_9FUSO

  • Protein
    Phosphoribosylglycinamide formyltransferase
  • Gene
    purN
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide from N1-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.

Features

Showing features for binding site, active site, site.

TypeIDPosition(s)Description
Binding site12-14N1-(5-phospho-beta-D-ribosyl)glycinamide (UniProtKB | ChEBI)
Binding site54(6R)-10-formyltetrahydrofolate (UniProtKB | ChEBI)
Binding site95(6R)-10-formyltetrahydrofolate (UniProtKB | ChEBI)
Active site97Proton donor
Site138Raises pKa of active site His

GO annotations

AspectTerm
Molecular Functionphosphoribosylglycinamide formyltransferase activity
Biological Process'de novo' IMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoribosylglycinamide formyltransferase
  • EC number
  • Alternative names
    • 5'-phosphoribosylglycinamide transformylase
    • GAR transformylase
      (GART
      )

Gene names

    • Name
      purN
    • ORF names
      CI114_07745

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • P2_CP
  • Taxonomic lineage
    Bacteria > Fusobacteriota > Fusobacteriia > Fusobacteriales > Fusobacteriaceae > Fusobacterium

Accessions

  • Primary accession
    A0A2G9FPJ1

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-175Formyl transferase N-terminal

Sequence similarities

Belongs to the GART family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    185
  • Mass (Da)
    20,942
  • Last updated
    2018-01-31 v1
  • Checksum
    7880FAC2050A66F2
MFKIIVLVSGSGTNMLQLIKNDIKIDCIIADRECKAKNIADEYKIDFVLLNRDKEISKNLLKIFEERKPDLIVLAGFLSILDGEILEKYKNKIINIHPSLLPKYGGKGMYGLKVHQAVFENGDKESGCTVHYVTSDVDAGEIIAQDKVDISMAKSPEEIQKLVLEREWNLLPRVVKELIKKSINN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NPND01000023
EMBL· GenBank· DDBJ
PIM89829.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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