A0A2G4HZW6 · A0A2G4HZW6_9FLAO

  • Protein
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • Gene
    hppA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Requires K+ for maximal activity.

Features

Showing features for site.

TypeIDPosition(s)Description
Site485Determinant of potassium dependence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Molecular Functionpotassium ion binding
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • EC number
  • Alternative names
    • Membrane-bound sodium-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (Na(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      CK532_06535

Organism names

Accessions

  • Primary accession
    A0A2G4HZW6

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-28Helical
Transmembrane59-77Helical
Transmembrane89-110Helical
Transmembrane131-164Helical
Transmembrane278-299Helical
Transmembrane311-335Helical
Transmembrane355-375Helical
Transmembrane491-513Helical
Transmembrane519-542Helical
Transmembrane590-609Helical
Transmembrane615-638Helical
Transmembrane686-703Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    802
  • Mass (Da)
    84,070
  • Last updated
    2018-01-31 v1
  • Checksum
    C99FF8186BF74597
MTNDAIIYVIPLMGVIGLIVMAIKSAWVSKQDAGDKNMQELAGYIADGAMAFLKAEWKVLSIFVVFAAALLAYSGTIHEINGREIHSSWIISIAFIIGAVFSATAGYIGMKVATKANVRTTQAARTSLKQALKVSFTGGTVMGLGVAGLAVLGLGGLFIAFLSYFQDLGDNSVKTAIEVLTGFSLGAESIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDVRNPATIADNVGDNVGDVAGMGADLFGSYVATILATMVLGQEIEVTDKFNGLSPILLPMVICGFGILFSIVGTWFVRIKDDNSNVQNALNLGNWASMLITVIASYFIVMWMLPDGDIVLRSTVFTKMGVFNAILVGTIVGAVMSIVTEYYTAMGKGPVNAIIQQSSTGHATNIIAGLAVGMKSTVIPILTLAAGIVTAYYFAGLYGVAIAAAGMMATTAMQLAIDAFGPIADNAGGIAEMSQLPPEVRERTDNLDAVGNTTAATGKGFAIASAALTSLALFAAFVGIAGIDSIDIYKAPVLAGLFVGAMIPFIFSALCIQAVGKAAMEMVQEVRRQFREIPGIMEYTAKPEYEKCVAISTKASIREMMIPGAIALITPVLVGFIFGPEVLGGLLAGVTVSGVLMGIFQSNAGGAWDNAKKSFEKGVMINGEMFYKKSEPHKASVTGDTVGDPFKDTSGPSMNILIKLMSIVSLVIAPFIVGKTFGESNNQSKILMPSNCKSMSTCDMDKCATLSKEECRKMCEANLCDSSEKAACMAMYDSNGKFIGSPKSECSNESTCKEKNDTPCSKGDACCKSKKM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NSIM01000023
EMBL· GenBank· DDBJ
PHX91788.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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