A0A2G4HZW6 · A0A2G4HZW6_9FLAO
- ProteinPutative K(+)-stimulated pyrophosphate-energized sodium pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids802 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.
Catalytic activity
- Na+(in) + diphosphate + H2O = Na+(out) + 2 phosphate + H+Na+ (in)CHEBI:29101
+ CHEBI:33019 + CHEBI:15377 = Na+ (out)CHEBI:29101+ 2 CHEBI:43474 + CHEBI:15378
Cofactor
Activity regulation
Requires K+ for maximal activity.
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 485 | Determinant of potassium dependence | ||||
Sequence: A |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | potassium ion binding | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative K(+)-stimulated pyrophosphate-energized sodium pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales
Accessions
- Primary accessionA0A2G4HZW6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-28 | Helical | ||||
Sequence: IIYVIPLMGVIGLIVMAIKSAWV | ||||||
Transmembrane | 59-77 | Helical | ||||
Sequence: VLSIFVVFAAALLAYSGTI | ||||||
Transmembrane | 89-110 | Helical | ||||
Sequence: WIISIAFIIGAVFSATAGYIGM | ||||||
Transmembrane | 131-164 | Helical | ||||
Sequence: ALKVSFTGGTVMGLGVAGLAVLGLGGLFIAFLSY | ||||||
Transmembrane | 278-299 | Helical | ||||
Sequence: ILLPMVICGFGILFSIVGTWFV | ||||||
Transmembrane | 311-335 | Helical | ||||
Sequence: ALNLGNWASMLITVIASYFIVMWML | ||||||
Transmembrane | 355-375 | Helical | ||||
Sequence: AILVGTIVGAVMSIVTEYYTA | ||||||
Transmembrane | 491-513 | Helical | ||||
Sequence: FAIASAALTSLALFAAFVGIAGI | ||||||
Transmembrane | 519-542 | Helical | ||||
Sequence: YKAPVLAGLFVGAMIPFIFSALCI | ||||||
Transmembrane | 590-609 | Helical | ||||
Sequence: MMIPGAIALITPVLVGFIFG | ||||||
Transmembrane | 615-638 | Helical | ||||
Sequence: GLLAGVTVSGVLMGIFQSNAGGAW | ||||||
Transmembrane | 686-703 | Helical | ||||
Sequence: ILIKLMSIVSLVIAPFIV |
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length802
- Mass (Da)84,070
- Last updated2018-01-31 v1
- ChecksumC99FF8186BF74597