A0A2D4M9A1 · A0A2D4M9A1_9SAUR

Function

function

Constitutes the active form, which associates with RELA/p65 to form the NF-kappa-B p65-p50 complex to form a transcription factor. Together with RELA/p65, binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular FunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding
Biological Processsignal transduction

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Nuclear factor NF-kappa-B p105 subunit
  • Alternative names
    • Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Lepidosauria > Squamata > Bifurcata > Unidentata > Episquamata > Toxicofera > Serpentes > Colubroidea > Elapidae > Elapinae > Micrurus

Accessions

  • Primary accession
    A0A2D4M9A1

Subcellular Location

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, repeat, region.

TypeIDPosition(s)Description
Domain45-252RHD
Repeat536-568ANK
Repeat575-607ANK
Repeat644-676ANK
Repeat678-711ANK
Repeat712-744ANK
Region884-907Disordered

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    975
  • Mass (Da)
    107,029
  • Last updated
    2018-01-31 v1
  • Checksum
    C9C77D428ACD7219
MADENSYLLGMGDHQVYAMEHYPLGMNQLYNNTSMISTDLPLRTTDGPYLQIVEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICSYAGPAKVIVQLVTNGKHVHLHAHSLVGKHCEQGVCTVNAGPKDMVVGFPNLGILHVTKKKVLDTLEMRMIDACKKGYNPGLLVHSDLNYIQVEGGGERQLTEREREIIHQAAHQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLQPVLSDPIYDSKAPNASNLKIVRMDRTAGCVTGGEEVYLLCDKVQKDDIQIRFYEEDESGGVWEGFGDFSPTDVHRQFAIVFKTPKYRDVNITKAASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVLRKRQKLMPNFSDSFGGSGAGAAGGGMYGGVGGGGGGSSAGSGYGYPPYGFSSYGAMHFHSSTNKSGAGMKHGVSNGTPKRENQMCCDKKHNEKLKEKVEIEDRSKTSTGSVSEMEEDASANVHLQDAFFLEKAMELAKRHANALFDYAVTGDVKMLLAVQRPLTTVQDENGDNVLHLAIIHLHMELVKNLLEVIANMNTAAVLNVRNDLYQTPLHLAVITRQAGIVRALLGAGADVNLLDRHGNSVFHLAAQQGDEVALSTLLQHKEASVMRDLPNGDGLTVLHLAVIANSMPCLRLLLAVGVDVNIQEQKSGRTALHLAIEQGNISMAGCLLLEGDAFVDSVTYDGTTPLHIAAGRGSTKLAALLKAAGADPHIENFEPLFEEEDIKDNESEKIIPGTTPLDMATSWEVYDILSSKLCKSKAASEHLLIHGNMKDLNEDVKLQLYKLLEVPDLTKSWSMLAQKLGLGILNNAFRLSPSPSKTLLDNYEVSGGTVKELINALREMDYPEAVEIIEKRITSSSQSKQEKTKNDVLPLCDLPSPRTEQADEIRNFKFQDAESICDSGVEISLHKLSFTYSESFTNKTSINLKKKASGYGQDNSLPGKIEVT

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
IACM01077940
EMBL· GenBank· DDBJ
LAB29563.1
EMBL· GenBank· DDBJ
Transcribed RNA

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