A0A2A4IN99 · A0A2A4IN99_9SPIR

  • Protein
    Polyamine aminopropyltransferase
  • Gene
    speE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site31S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Binding site62spermidine (UniProtKB | ChEBI)
Binding site86spermidine (UniProtKB | ChEBI)
Binding site106S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Binding site137-138S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Active site156Proton acceptor
Binding site156-159spermidine (UniProtKB | ChEBI)
Binding site163S-methyl-5'-thioadenosine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionspermidine synthase activity
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyamine aminopropyltransferase
  • Alternative names
    • Putrescine aminopropyltransferase
      (PAPT
      )
    • Spermidine synthase
      (SPDS
      ; SPDSY
      ) (EC:2.5.1.16
      ) . EC:2.5.1.16 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      speE
    • ORF names
      KQ44_04485

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • G79
  • Taxonomic lineage
    Bacteria > Spirochaetota > Spirochaetia > Brachyspirales > Brachyspiraceae > Brachyspira

Accessions

  • Primary accession
    A0A2A4IN99

Proteomes

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-238PABS

Sequence similarities

Belongs to the spermidine/spermine synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    286
  • Mass (Da)
    33,257
  • Last updated
    2017-12-20 v1
  • Checksum
    4AAA3935726F5EC1
MELWYTENHTEESKFSIKVEKQLYSAQTNFQRIDVFESKEFGKFFTLDGLIMVTEKDEFIYHDMIVHVPMASNGNIKNVLVIGGGDGGTVRELTRYKTIEKIDMVEIDEQVVEVCKKYFPSTTSGLSDKRVSLYFQDGLKFVRDAKEGEYDLIIVDSTDPFGPGEGLFTREFYGNCHKALSKDGILVNQHECPYYSDYAYNMQRAHRNIYETFNIAKVYQAHIPTYPSGHWLFGFASKTIDPIKDLKEEEWLKHNLDTKYYNLDIHKGCFALPTYVKKLLEQSHHE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JQIU01000008
EMBL· GenBank· DDBJ
PCG19372.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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